Article - 29/04/2013 Bioactive plant foods: plant substances against cancer stem cells Many findings indicate that the consumption of cruciferous vegetable plants rich in mustard oil glycosides has a cancer-inhibiting effect. Researchers from Heidelberg have now shown that sulforaphane, a broccoli mustard oil, blocks a signalling pathway that makes tumour stem cells resistant to cytotoxic drugs. The administration of sulforaphane can prevent therapy resistance and metastasis of pancreatic cancer in animal models.https://www.gesundheitsindustrie-bw.de/en/article/news/bioactive-plant-foods-plant-substances-against-cancer-stem-cells
Article - 20/06/2016 New diagnostic tool for greater health safety when dealing with multidrug-resistant pathogens Infections with antibiotic-resistant bacteria and diseases such as breast or colon cancer are among the major causes of death worldwide. Early diagnosis is therefore key for the identification of people affected and for providing immediate therapy. The R&D service provider Hahn-Schickard and its partners are currently working on the development of a rapid and simple diagnostic system that can detect life-threatening infections and cancer at…https://www.gesundheitsindustrie-bw.de/en/article/news/new-diagnostic-tool-for-greater-health-safety-when-dealing-with-multidrug-resistant-pathogens
Press release - 26/04/2011 Green Light for Four New Centres of Health Research The decision has been taken: The German Centres of Health Research which are to be set up in the areas of infectious diseases, cardiovascular diseases, lung diseases and cancer will involve more than 100 universities, university hospitals and non-university research institutions at 27 locations. Federal Research Minister Annette Schavan decided on the funding of four new centres on Friday after considering recommendations submitted by panels of…https://www.gesundheitsindustrie-bw.de/en/article/press-release/green-light-for-four-new-centres-of-health-research
Article - 02/12/2008 Cancer cells do not like rocket salad Isothiocyanates which are substances found in vegetables such as rocket kohlrabi or mustard promote good health. Dr. Evelyn Lamy and her team at the Freiburg University Hospital found out that isothiocyanates lead to considerably fewer DNA strand breaks.https://www.gesundheitsindustrie-bw.de/en/article/news/cancer-cells-do-not-like-rocket-salad
Press release - 14/01/2009 IND Approval for CureVac CureVac Receives IND Approval from the FDA to start its Phase I/IIa mRNA Vaccine Clinical Trial in Prostate Cancer. https://www.gesundheitsindustrie-bw.de/en/article/press-release/ind-approval-for-curevac
Article - 30/08/2010 Diagnostics for the early detection of cervical cancer The Pap test is regarded as the most successful test for cancer ever, and has saved the lives of many women. However, the test is associated with several weaknesses. The Heidelberg-based in vitro diagnostics company mtm laboratories AG develops and commercialises highly sensitive and highly specific immunochemical tests that provide greater reliability. These tests have the potential to revolutionise the early detection of cervical cancer.https://www.gesundheitsindustrie-bw.de/en/article/news/diagnostics-for-the-early-detection-of-cervical-cancer
Press release - 21/05/2010 The road to individualized tumour vaccines What are the typical cancer cell characteristics that our immune system is directed against? Using a new biochemical method, scientists from the Neurosurgery Department of the Heidelberg University Hospital and the German Cancer Research Centre (Deutsches Krebsforschungszentrum, DKFZ) are now able to answer this question for each individual patient. The method is expected to help identify new target structures for individualized tumour vaccines. https://www.gesundheitsindustrie-bw.de/en/article/press-release/the-road-to-individualized-tumour-vaccines
New edition - 24/05/2019 Tumour metastasis Cancer is usually not curable when metastases have formed in the body. Metastases are often resistant to drugs that have successfully eliminated the primary tumour. The basic features of the complex process of metastasis are now known, but many details still remain elusive. Intensive research activities are focusing on new therapeutic concepts aimed at developing effective anti-metastatic therapies.https://www.gesundheitsindustrie-bw.de/en/article/dossier/tumour-metastasis
Article - 22/03/2019 Personalised therapies for treating metastasing breast cancer Breast cancer is characterised by broad genetic diversity. Successful treatment is made even more difficult by the fact that, in advanced breast cancer, the properties of metastases often differ significantly from the primary tumour. The Heidelberg CATCH study is now collecting genetic profiles from patients' metastasis tissue samples, which can be used to tailor therapy to individual requirements.https://www.gesundheitsindustrie-bw.de/en/article/news/personalisierte-therapieansaetze-bei-metastasiertem-brustkrebs
Press release - 20/05/2008 Bookmarks in the human book of life Histone acetyltransferases HATs and their antagonists the histone deacetylases are important enzymes in epigenetic gene regulation. Scientists discovered new HAT inhibitors that are now being investigated for their potential as anti-cancer drugs.https://www.gesundheitsindustrie-bw.de/en/article/press-release/bookmarks-in-the-human-book-of-life
Press release - 12/10/2011 Dioxin-like Chemical Messenger Makes Brain Tumors More Aggressive Scientists from German Cancer Research Center and Heidelberg University have discovered a new dioxin receptor-coupled metabolic pathway which weakens the immune system and promotes the growth of malignant gliomas. Glioma is the most frequent and most malignant brain tumor in adults. In Germany, about 4,500 people are newly diagnosed with glioma every year.https://www.gesundheitsindustrie-bw.de/en/article/press-release/dioxin-like-chemical-messenger-makes-brain-tumors-more-aggressive
Press release - 18/04/2012 immatics appoints Dr. Rainer Kramer as Chief Business Officer immatics biotechnologies GmbH, a clinical-stage biopharmaceutical company developing therapeutic vaccines that are active against cancer, today announced the appointment of Dr. Rainer Kramer as Chief Business Officer (CBO) with immediate effect. In this newly created role, Dr. Kramer will lead immatics’ Business Development Unit in order to create optimal value from the Company’s pipeline of therapeutic cancer vaccines.https://www.gesundheitsindustrie-bw.de/en/article/press-release/immatics-appoints-dr-rainer-kramer-as-chief-business-officer
Press release - 15/10/2013 Biotech financing in Baden-Württemberg: immatics raises 34 million Euros The immatics biotechnologies GmbH, a clinical-stage biopharmaceutical company developing advanced multi-peptide cancer vaccines that are active against cancer, today announced that it has closed a 34 million Euros Series D financing round. The funding round was supported by existing investors including dievini Hopp Biotech holding, Wellington Partners, MIG-advised funds and AT Impf GmbH. Under the terms of the fundraising, immatics will receive…https://www.gesundheitsindustrie-bw.de/en/article/press-release/biotech-financing-in-baden-wuerttemberg-immatics-raises-34-million-euros
Article - 06/05/2013 HeLa, a human bauplan in the Petri dish Scientists from EMBL have recently sequenced the genome of HeLa cells, which are the world’s most commonly used human cell line. They found that the HeLa genome and that of normal human cells reveal striking differences, caused by chromothripsis and other aberrations. Some evolutionary researchers believe that HeLa cells are developing a new human bauplan as they adapt to cultivation in the Petri dish. https://www.gesundheitsindustrie-bw.de/en/article/news/hela-a-human-bauplan-in-the-petri-dish
Article - 30/06/2014 Targeting epigenetic DNA modifications for the diagnosis of cancer Epigenetic DNA modifications have been shown to play a role in carcinogenesis and are therefore a promising target for the early detection of cancer. Dr. Daniel Summerer and his research group at the University of Konstanz have developed a method that enables the direct and site-specific identification of epigenetic changes. The method represents a new approach in the field of epigenetic analysis as well as a major step towards simpler cancer…https://www.gesundheitsindustrie-bw.de/en/article/news/targeting-epigenetic-dna-modifications-for-the-diagnosis-of-cancer
Article - 31/03/2014 TherapySelect – Identifying Susceptibility to Cancer Therapy TherapySelect Dr. Frank Kischkel is an innovative biotechnology company based in Heidelberg, Germany, with a special focus on the development, validation and application of diagnostic tests for cancer patients. The company’s proprietary CTR-Test® uses patients’ cancer cells to determine the tumor’s susceptibility to treatment with cytostatic drugs. This knowledge helps identify ineffective drugs prior to treatment as well as reduce adverse drug…https://www.gesundheitsindustrie-bw.de/en/article/news/therapyselect-identifying-susceptibility-to-cancer-therapy
Press release - 16/04/2008 Effective Cancer Immune Therapy Through Order in the Blood Vessels Researchers at the German Cancer Research Center have discovered a key molecule that is responsible for the immature structure of blood vessels in malignant tumors. If this molecule is switched off in mice vessels normalize so that immune cells are better able to get to the tumor tissue.https://www.gesundheitsindustrie-bw.de/en/article/press-release/effective-cancer-immune-therapy-through-order-in-the-blood-vessels
Article - 09/03/2008 Successful attack on resistant tumour cells In laboratory experiments Dr. Anja Apel from the University Hospital in Heidelberg proved that cancer cells that are resistant to radiation therapy can be made to become susceptible to this kind of treatment again by blocking the cells own recycling system.https://www.gesundheitsindustrie-bw.de/en/article/press-release/successful-attack-on-resistant-tumour-cells
Press release - 21/05/2010 The molecular network of “death receptors” on trial The international ApoNET research project, which is part of a European-wide systems biology initiative, is coordinated by the Mannheim Medical Faculty at the University of Heidelberg. ApoNET researchers use modern genome sequencing methods and computer models to gain a better understanding of apoptosis networks in liver cells. The project is funded by the German Federal Ministry of Education and Research and the European Union with 1.7 million…https://www.gesundheitsindustrie-bw.de/en/article/press-release/the-molecular-network-of-death-receptors-on-trial
Article - 18/08/2014 The use of human genes as medical products In contrast to medications used for treating disease, gene therapy does not use chemical agents to alleviate or cure disease symptoms. Instead, it involves the introduction of a normal copy of a mutated gene to restore the function of a protein. Gene therapy could also be described as a way of restoring the body’s self-healing process. It is an extremely smart idea that enables the sustainable treatment of diseases which cannot usually be…https://www.gesundheitsindustrie-bw.de/en/article/news/the-use-of-human-genes-as-medical-products
Article - 05/03/2019 Vaccination against oncogenic Epstein-Barr viruses Almost all humans are infected with Epstein-Barr viruses (EBV), which are linked to the development of benign diseases such as infectious mononucleosis as well as several cancers. Scientists from the German Cancer Research Center have developed a new strategy for creating a vaccine that targets different EBV virus life phases and has the potential to provide effective protection against EBV infection.https://www.gesundheitsindustrie-bw.de/en/article/news/vaccination-against-oncogenic-epstein-barr-viruses
Event - 17/09/2020 - 18/09/2020 2nd International Conference on Cancer Prevention online, Registration deadline: 24/08/2020https://www.gesundheitsindustrie-bw.de/en/event/2nd-international-conference-cancer-prevention
Article - 07/03/2017 KiTZ: Hopp Children’s Tumour Center at NCT Heidelberg The Heidelberg University Hospital and the DKFZ have established the "Hopp Children's Tumor Center at NCT Heidelberg" (KiTZ) where doctors, scientists, nursing staff and other specialists work side by side on new diagnostic and therapeutic options to help children with cancer.https://www.gesundheitsindustrie-bw.de/en/article/news/kitz-hopp-childrens-tumour-center-at-nct-heidelberg
Article - 28/04/2014 Sciomics: antibody microarrays and their broad range of applications Sciomics GmbH is a start-up biotech from Heidelberg with a special focus on protein microarrays. Sciomics produces complex, high-density antibody microarrays for cancer-relevant proteins and offers services for medical research, diagnostics and the industry, including biomarker screening, the verification of biomarker candidates, the analysis and localization of drug targets and their signalling pathways as well as the characterization of…https://www.gesundheitsindustrie-bw.de/en/article/news/sciomics-antibody-microarrays-and-their-broad-range-of-applications
Article - 15/12/2009 Arming the immune system against cancer The theory that immune cells are able to attack tumours has long been a theory with only a minority of supporters. However, this theory is currently experiencing a renaissance. In the future, it might even be possible to specifically alter T-lymphocytes in order to improve their ability to identify and destroy certain tumour types. Prof. Dr. Hanspeter Pircher and his team at the Freiburg University Medical Centre are focusing on the development…https://www.gesundheitsindustrie-bw.de/en/article/news/arming-the-immune-system-against-cancer