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  • Article - 25/04/2016 Trumpp_Andreas.jpg

    Pancreatic cancer and its resistance to therapy

    Pancreatic tumours are among the cancers with the worst prognosis. In many cases they are resistant to treatment. Prof. Dr. Andreas Trumpp and his colleagues from the DKFZ and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine HI-STEM have discovered that the reason why some pancreatic tumours are so resistant to treatment is down to larger quantities of the enzyme CYP3A5 in subtypes of pancreatic cancer. Molecular…

    https://www.gesundheitsindustrie-bw.de/en/article/news/pancreatic-cancer-and-its-resistance-to-therapy
  • Article - 14/04/2016 B/w electron microscope image of a fungus of the genus Candida.

    Rapid and unambiguous detection of infection in a miniature laboratory

    In cooperation with industrial partners, researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart have spent many years developing innovative diagnostic tools for use in infection biology. Among these are microsystems that combine complete test procedures on a “lab-on-a-chip” (LOC) and enable simultaneous analysis of several thousand parameters relatively quickly and with little effort. The scientists…

    https://www.gesundheitsindustrie-bw.de/en/article/news/rapid-and-unambiguous-detection-of-infection-in-a-miniature-laboratory
  • Retrospective Meet & Match Pharmaceutical Process Technology - 07/04/2016 DSC_0031.jpg

    Speed dating for Pharmaceutical Process Technology – a business flirt at Bosch

    The speed dating format is no longer just a popular and simple dating method for lonely hearts, but has also become a rewarding way for establishing new business contacts and connections quickly and efficiently. BIOPRO Baden-Württemberg chose speed networking, as speed dating is called in the corporate world, for its recent Meet & Match event on pharmaceutical process technology, which took place on 15th March 2016 with the support of Bosch…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/speed-dating-for-pharmaceutical-process-technology-a-business-flirt-at-bosch
  • Article - 29/03/2016 Photo of five zebrafish.

    The zebrafish can mend its own heart

    In adults, cells such as nerve or cardiac muscle cells have lost the ability to regenerate. This is why myocardial infarction is so dangerous – damaged cardiac muscle cells do not grow back and scar tissue forms in their place. Prof. Dr. Gilbert Weidinger and an international team of researchers have deciphered a mechanism responsible for the regeneration of the zebrafish heart.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-zebrafish-can-mend-its-own-heart
  • Medical technology - 14/03/2016 Experimenteller_Interventionsraum_mit_mobilen_Rontgengerat_Monitoren_und_OP-Tisch_an_dem_der_Interventionsassistent_herangefahren_werden_kann.jpg

    The operating room of the future: minimally invasive and future-oriented intervention techniques

    Being able to diagnose and treat tumour patients in just a few hours is just one of the many promising goals of the Fraunhofer Project Group for Automation in Medicine and Biotechnology (PAMB). The overall goal of the Intervention and Therapy research group is to take innovative technologies for diagnostic and therapeutic interventions from laboratory development to prototype production for use in clinical trials.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-operating-room-of-the-future-minimally-invasive-and-future-oriented-intervention-techniques
  • Article - 07/03/2016 Schematic representation of the methods: i) Structural data are generated by multiple methods, predominantly mass spectrometry, and are used alongside available data from databases. ii) The system is represented as a collection of rigid bodies and beads on a flexible string. iii) An ensemble of structures that are consistent with the experimental data is obtained by conformational sampling. iv) The ensemble is analysed and validated.

    Looking at the control of cellular homeostasis

    Many biological processes that occur in our body are driven and controlled by protein complexes. In order to better understand these processes, biochemist Prof. Dr. Florian Stengel from the University of Konstanz is developing methods that will eventually make it possible to study the architecture, interactions and general dynamics of intact protein complexes quantitatively and in detail. Stengel combines structural mass spectrometry methods with…

    https://www.gesundheitsindustrie-bw.de/en/article/news/looking-at-the-control-of-cellular-homeostasis
  • Article - 03/03/2016 Schematic showing how liquid biopsies can be used to analyse freely circulating (fc) DNA in the blood. The schematic shows the technique as applied to GIST (gastrointestinal stroma tumours).

    Liquid biopsies – beacons of hope for cancer diagnosis?

    Researchers around the world, including researchers from the Freiburg University Medical Center, are working on developing simple blood tests, so-called liquid biopsies, that can be used to obtain accurate information about tumour staging and the progress of therapy. An international liquid biopsy symposium was held in Freiburg in October 2015 and has produced valuable insights.

    https://www.gesundheitsindustrie-bw.de/en/article/news/liquid-biopsies-beacons-of-hope-for-cancer-diagnosis
  • Article - 02/02/2016 Innovation.jpg

    EU consortium to speed up innovations in the healthcare sector

    EIT Health is a large-scale European project launched in December 2014 that aims to help people in Europe to live a healthier life and stay active as they grow older. The consortium brings together 140 leading companies and institutions from 14 European countries and has a total budget of two billion euros. It is one of the largest networks worldwide in the healthcare sector.

    https://www.gesundheitsindustrie-bw.de/en/article/news/eu-consortium-to-speed-up-innovations-in-the-healthcare-sector
  • Article - 21/01/2016 The photo shows a man evaluating a technological work step.

    Genome research as information research

    DNA sequencing has become indispensable in modern science. Innovative advances that will bring about changes in the life sciences and medicine are due to rapid developments in genome analysis technologies. In the interview below, Peter Pohl, CEO and co-founder of GATC Biotech AG, explains why DNA sequencing will become even more important in future.

    https://www.gesundheitsindustrie-bw.de/en/article/news/genome-research-as-information-research
  • Article - 17/11/2015 Electron microscope image of crystalline precipitates secreted by Halomonas bacteria. The precipitates are stained blue.

    Novel hydrogels as functional materials

    In the ”NanoBioMater”project house, researchers from the University of Stuttgart are working to develop novel hydrogels with integrated biocompatible scaffold structures. Their aim is to make the materials suitable for producing innovative components for environmental and food analytics as well as medical applications. The hydrogels could potentially be used in diagnostic biosensors and the controlled release of medical compounds.

    https://www.gesundheitsindustrie-bw.de/en/article/news/novel-hydrogels-as-functional-materials
  • Telemedicine - 19/10/2015 44513-WEB-bvmed-bilderwelt-ehealth-diabetes-1.jpg

    Medical apps – potential helpers for physicians and patients

    Can smartphones become health counsellors for patients or diagnostic tools for doctors? The answer is yes, at least technically. However, health apps that comply with valid medical device regulations are still rather rare in Germany. Many health insurance companies are reluctant to pay for the use of these modern tools because the legal framework is inadequate and doctors are not yet fully capable of using them. Nevertheless, the use of such…

    https://www.gesundheitsindustrie-bw.de/en/article/news/medical-apps-potential-helpers-for-physicians-and-patients
  • Article - 24/09/2015 ESEQuant_LR3.jpg

    New test system for detection of HPV-related oral cavity cancers

    The number of people suffering from oral or oropharyngeal cancer is rising steadily. The major cause of these cancers is human papillomaviruses (HPV) that colonise the oral cavity, where they are difficult to detect. QIAGEN Lake Constance GmbH from Stockach, in cooperation with Abviris Deutschland GmbH, has developed a new test system to improve the detection of oral HPV. This new system enables rapid and reliable quantitative detection of…

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-test-system-for-detection-of-hpv-related-oral-cavity-cancers
  • Article - 21/09/2015 Schematic of a test strip (horizontal) illustrating the principle of competitive immunoassays that play a key role in detecting small analytes with a single epitope. The flow direction in the capillary is from left to right. Analytes (small molecules) are added to the test strip (on the left), which will initially come into contact with nanoparticle-antibody conjugates, then on a test and control area.

    Hans-Peter Deigner: "Optimisation of lateral flow assays using nanoparticles."

    Nanoparticles are already used in many materials and areas, ranging from textiles to scientific and medical research. The global scientific community is keenly interested in nanoparticle research and Prof. Dr. Hans-Peter Deigner, professor in the Faculty of Medical and Life Sciences at Furtwangen University of Applied Sciences (HFU) is no exception. Deigner works on optimising nanoparticles for application in lateral flow assays. As well as…

    https://www.gesundheitsindustrie-bw.de/en/article/news/hans-peter-deigner-optimisation-of-lateral-flow-assays-using-nanoparticles
  • Pharmaceutical research and life sciences profit from unique biosensor technology - 18/09/2015 biametrics_Logo.jpg

    Biametrics GmbH concludes financing round with 3.1 Million Euro

    Biametrics GmbH today announced the completion of their most recent financing round with €3.1 Million. Partners of the A Series Investment were LBBW Venture GmbH, MBG Mittelständische Beteiligungsgesellschaft BW, and KfW Bankengruppe. Together with seed investors HTGF and Seedfonds BW, they are aiming to accelerate the expansion of Biametrics’ bioanalytical business activities to an international level. The fresh capital will facilitate the…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/biametrics-gmbh-concludes-financing-round-with-31-million-euro
  • Article - 15/06/2015 Schematic presentation of molecular diagnostic procedures and bioinformatic analyses used for cancer patients.

    Centre for Personalised Medicine in Tübingen - developing tailor-made treatments for patients

    Since January 2015, Tübingen has been home to a Centre for Personalised Medicine (ZPM). Twenty-three institutes and hospitals have joined forces to improve diagnosis of disease and develop individualised treatments for patients with a variety of diseases. In parallel, the centre also develops new diagnostic strategies. This means, for example, that data derived from the analysis of the entire genetic material of cells, proteins and metabolic…

    https://www.gesundheitsindustrie-bw.de/en/article/news/centre-for-personalised-medicine-in-tuebingen-developing-tailor-made-treatments-for-patients
  • Overview

    Diagnostics

    The latest articles, press releases and dossiers on diagnostics in Baden-Württemberg

    https://www.gesundheitsindustrie-bw.de/en/article/diagnostics
  • The Baden-Württemberg healthcare industry

    Medical technology

    Medical technology is indispensible for human health and contributes a great deal to improving the quality of our lives. The field of medical technology covers many areas. These range from simple disposable products and consumables such as dressing materials and other clinical supplies, to IT-related telemedicine, homecare and eHealth systems as well as high-technology and innovative robotics, imaging, diagnostics and life-support systems. 842…

    https://www.gesundheitsindustrie-bw.de/en/location/medtech
  • The Baden-Württemberg healthcare industry

    The pharmaceutical industry

    Baden-Württemberg is Germany’s largest pharma location. In addition to industry giants such as Roche, GlaxoSmithKline and Boehringer Ingelheim, Baden-Württemberg is home to a large number of small- and medium-sized pharmaceutical companies and biotech companies with pharmaceutical research and development.

    https://www.gesundheitsindustrie-bw.de/en/location/pharma
  • The Baden-Württemberg healthcare industry

    The biotechnology sector

    Baden-Württemberg is currently home to 188 biotechnology companies. In addition to dedicated biotechnology companies, this also includes bioinformatics, diagnostics and analytics companies that use modern biotechnology methods or focus on biotechnological production.

    https://www.gesundheitsindustrie-bw.de/en/location/biotech
  • Article - 23/03/2015 The photo shows the device described in the text. It is shown pipetting a cell suspension into a microtitre plate with 96 wells.

    cytena GmbH facilitates the separation of single cells

    cytena GmbH, a start-up company which was spun out from the Department of Microscystems Engineering (IMTEK) at the University of Freiburg in 2014, has developed a device that enables single cells to be deposited safely and gently using a single-cell printer called cy-Clone. Once processed, the cells can be used to study tumour heterogeneity and to create clonal cell lines for producing antibodies.

    https://www.gesundheitsindustrie-bw.de/en/article/news/cytena-gmbh-facilitates-the-separation-of-single-cells
  • Article - 26/01/2015 Photo showing a laboratory involved in the TTU "Malaria". The photo shows two scientists working at a work bench.

    Pooling efforts against infectious diseases in Germany

    Over 150 scientists at various locations throughout Germany work together as part of the German Centre for Infection Research (DZIF). The centre focuses on the development of new diagnostic, preventive and therapeutic methods for treating infectious diseases. Scientists from the University and University Hospital of Tübingen and the Max Planck Institute for Developmental Biology are also part of the project. The researchers from Tübingen are…

    https://www.gesundheitsindustrie-bw.de/en/article/news/pooling-efforts-against-infectious-diseases-in-germany
  • Article - 26/01/2015 22698_de.jpg

    A biomarker as indicator for the likelihood of developing aggressive prostate cancer

    Overexpression of the protein BAZ2A, which leads to alterations in epigenetic patterns, increases the malignant properties of tumour cells, including their mobility and their ability to form metastases. The findings of a team of researchers from Heidelberg, Zurich and Hamburg may have led to the discovery of an urgently needed prognostic biomarker that would make it possible to differentiate aggressive prostate cancer from the less malignant…

    https://www.gesundheitsindustrie-bw.de/en/article/news/a-biomarker-as-indicator-for-the-likelihood-of-developing-aggressive-prostate-cancer
  • Article - 19/01/2015 22608_de.jpg

    Kay Gottschalk and the physics of cells

    You learn a great deal about the physical aspects of cells when you talk to Prof. Dr. Kay-E. Gottschalk. For example, their ability to react as solid and liquid, to adapt their environment to suit themselves and to exert and respond to forces. The 42-year-old has great respect for the smallest of living units, i.e. cells, which he calls smart composite materials. Working on the boundaries of medicine, biology, chemistry and physics, Gottschalk…

    https://www.gesundheitsindustrie-bw.de/en/article/news/kay-gottschalk-and-the-physics-of-cells

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