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  • Article - 31/07/2010 Dr. Christian Riedel sitting in front of his computer in his office.

    Christian Riedel – an outstanding bifidobacteria researcher

    The 37-year-old microbiologist Christian Riedel was recently awarded the Science Prize of the city of Ulm for his basic research on bifidobacteria. Riedel who is the head of a group of 12 junior researchers at the University of Ulm has shown that bifidobacteria exert an inhibitory effect on chronic bowel inflammation. The researcher hopes to have identified the underlying molecular mechanisms within the next 12 months.

    https://www.gesundheitsindustrie-bw.de/en/article/news/christian-riedel-an-outstanding-bifidobacteria-researcher
  • Article - 28/06/2010 The schematic shows a protein complex with different areas.<br />

    ATG:biosynthetics GmbH – Modular molecular systems of the future

    ATGbiosynthetics GmbH based in Merzhausen close to Freiburg produces biological systems that can combine gene constituents following a construction kit principle. The company provides the pharmaceutical industry and basic researchers with products that have specifically chosen properties.

    https://www.gesundheitsindustrie-bw.de/en/article/news/atg-biosynthetics-gmbh-modular-molecular-systems-of-the-future
  • Article - 11/06/2010 Dr. Christoph Mayer in the microbiology laboratory at the University of Constance. He is holding a test tube over a gas burner.<br /> <br />

    Recycling of bacterial cell wall constituents

    Bacterial cells are focused on growth and proliferation. These processes are initiated by cellular enzymes that break up the cell wall material murein introduce new material and degrade material that is no longer needed. And all this in large amounts about 50 per cent of murein are degraded and newly formed turnover per cell generation. Dr. Christoph Mayer and his team from the University of Constance have shown that the cells carry out effective…

    https://www.gesundheitsindustrie-bw.de/en/article/news/recycling-of-bacterial-cell-wall-constituents
  • Press release - 07/06/2010

    Addition of renowned experts to Medical Advisory Board and achievement of international quality standards generate added optimism

    With a € 1.5 Mio Second Closing, Curetis has now increased its Series A financing round to € 20 Mio. This additional financing will enable Curetis to complete the development of its innovative diagnostic products through to market entry. Quality Certification for its diagnostic product development represents an additional milestone in Curetis' commercial strategy. At the same time, Curetis has added internationally recognized expertise in…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/addition-of-renowned-experts-to-medical-advisory-board-and-achievement-of-international-quality-stan
  • Article - 19/04/2010 The microscope image shows six spherical structures closely attached to each other.<br />

    Trying to get a virus to reveal its tricks

    The Thogoto virus is an exotic virus that presents virtually no danger to humans. A group of virologists led by Prof. Dr. Georg Kochs at the Freiburg University Medical Centre are using the virus as model system for its particular suitability in certain experiments. The group is investigating how the virus evades the antiviral defence of the infected host.

    https://www.gesundheitsindustrie-bw.de/en/article/news/trying-to-get-a-virus-to-reveal-its-tricks
  • Article - 29/03/2010 The photo shows a grey, blossom-like structure with hundreds of small spheres.<br />

    A ray of light for fungi

    Breaking through the protective darkness of the soil can be very uncomfortable for fungi because it requires them to adapt quickly to UV radiation or moisture fluctuations. But how do they know that they are on the soil surface? An important parameter is light. Researchers led by Prof. Dr. Reinhard Fischer at the Karlsruhe Institute of Technology (KIT) are investigating how the mould Aspergillus nidulans perceives light and how this governs its…

    https://www.gesundheitsindustrie-bw.de/en/article/news/a-ray-of-light-for-fungi
  • Article - 15/03/2010 The photo shows six wells containing four brain slices each.<br />

    Borna disease virus and cell death in the brain

    A research group led by Prof. Dr. Bernd Heimrich at the University of Freiburg is investigating how the Borna disease virus can alter characteristic neuronal circuits and destroy the hippocampal nerve cells. The scientists have developed an extremely practical petri dish test system. Their results show which cell types sustain the most damage following infection and also give indications as to how apoptosis cell death can be prevented.

    https://www.gesundheitsindustrie-bw.de/en/article/news/borna-disease-virus-and-cell-death-in-the-brain
  • Article - 15/03/2010 10873_de.jpg

    Andreas Diefenbach: A molecular approach to disease mechanisms

    Prof. Dr. Andreas Diefenbach began his academic career as a philosophy student. Nowadays, the immunologist at the Freiburg University Medical Centre investigates how cells of the innate immune system fight off cancer and infections. He believes that, in contrast to all other subjects, immunology is an area that very much focuses on concepts. Diefenbach’s research frequently gives rise to situations needing new paradigms.

    https://www.gesundheitsindustrie-bw.de/en/article/news/andreas-diefenbach-a-molecular-approach-to-disease-mechanisms
  • Article - 15/03/2010 10842_de.jpg

    Cystic fibrosis therapy is making good progress

    Thirty years ago cystic fibrosis CF formerly also known as mucoviscidosis was considered to be a disease that only affected children. Hardly any children with this hereditary metabolic disease ever reached early adulthood. Since then both the therapy and the life expectancy of CF patients have improved considerably. Dr. Gerd Döring from Tübingen is investigating the occurrence of respiratory tract defects that are common in CF patients.

    https://www.gesundheitsindustrie-bw.de/en/article/news/cystic-fibrosis-therapy-is-making-good-progress
  • Article - 13/03/2010 10874_de.jpg

    Assembling life from building blocks?

    As part of its “Bioethics Forum”, the German Ethics Council recently held a meeting in Berlin to inform the public about the fundamentals of synthetic biology and potential ethical problems and consequences in terms of our ideas about life and mankind in general arising from the progress made in this new field of research.

    https://www.gesundheitsindustrie-bw.de/en/article/news/assembling-life-from-building-blocks
  • Article - 22/02/2010 10696_de.jpg

    Treasure trove of data from Ulm helps in the understanding of community-acquired pneumonia

    CAP community-acquired pneumonia is a common type of pneumonia that mainly affects young and old people. In Germany around 800000 people contract CAP every year and almost one third has to be admitted to hospital exceeding the number of admissions due to cardiac infarction or stroke. The CAPNETZ competence network which up until recently was funded by the German government is gradually shedding light on a hitherto little known disease.

    https://www.gesundheitsindustrie-bw.de/en/article/news/treasure-trove-of-data-from-ulm-helps-in-the-understanding-of-community-acquired-pneumonia
  • Article - 11/02/2010 10669_de.jpg

    New interfaculty institute combines excellent basic research with clinical application

    Infection research is one of the major scientific beacons of the University of Tübingen, where the close thematic collaboration between scientists and doctors is the key to success. The close collaboration between scientists and doctors at the university also played a key role in the setting up of two collaborative research centres (SFB). With the recent establishment of the Interfaculty Institute for Microbiology and Infection Medicine (IMIT),…

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-interfaculty-institute-combines-excellent-basic-research-with-clinical-application
  • Article - 15/12/2009 10453_de.jpg

    Arming the immune system against cancer

    The theory that immune cells are able to attack tumours has long been a theory with only a minority of supporters. However, this theory is currently experiencing a renaissance. In the future, it might even be possible to specifically alter T-lymphocytes in order to improve their ability to identify and destroy certain tumour types. Prof. Dr. Hanspeter Pircher and his team at the Freiburg University Medical Centre are focusing on the development…

    https://www.gesundheitsindustrie-bw.de/en/article/news/arming-the-immune-system-against-cancer
  • Article - 01/12/2009 10267_de.jpg

    Ralf Takors – a bio-engineer

    Multidisciplinary talent, people who can combine biological knowledge in an outstanding way with engineering, is in great demand. Ralf Takors, who has been head of the Institute of Bioprocess Engineering (IBVT) at the University of Stuttgart since July 2009, is one such talent.

    https://www.gesundheitsindustrie-bw.de/en/article/news/ralf-takors-a-bio-engineer
  • Article - 10/09/2009 Trigger factor (red) in a complex formed with the ribosome (grey): Trigger factor binds to the ribosomal protein L23 (green) and bends over the ribosomal tunnel exit and hence over the nascent protein (yellow).

    Chaperone research using baker’s yeast and bacteria

    Protein misfolding and aggregation can lead to neurodegenerative diseases such as Alzheimers. Prof. Elke Deuerling at the University of Constance is investigating the molecular helpers the chaperones and the key role that they have in protein folding. Deuerling uses the bakers yeast Saccharomyces cerevisiae and the bacterium Eschericia coli for her studies. Her studies involving E. coli have now shown that ribosome-associated chaperones are…

    https://www.gesundheitsindustrie-bw.de/en/article/news/chaperone-research-using-baker-s-yeast-and-bacteria
  • Press release - 09/09/2009 09612_de.jpg

    “Road trip” to the Lake Constance

    American scientists from the J. Craig Venter Institute JCVI have recently visited the Institute of Limnology at the University of Constance at Lake Constance. The visit was part of the Sorcerer II Expedition which is a unique global mission to sample and discover the diversity of microorganisms and their role in global substance flows.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/road-trip-to-the-lake-constance
  • Press release - 04/09/2009 Photo of the awarded Dirk Linke.

    Motivation impetus for researcher on bacteria

    Dirk Linke 37 has been awarded the Advancement Award of the German Society for Hygiene and Microbiology Deutsche Gesellschaft für Hygiene und Mikrobiologie DGHM. The award includes prize money of 2500 Euro and will be presented on September 20th 2009 during the 61st Annual Meeting of the DGHM in Göttingen.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/motivation-impetus-for-researcher-on-bacteria
  • Article - 17/08/2009 Artistic presentation of an apoptotic cell – painted by the Yale University student, Alex Marzuka, who sold the picture in an auction for the benefit of bone marrow donations.

    A kiss of death for cells

    Prof. Dr. Peter Krammer of the German Cancer Research Centre has considerably contributed to clarifying the apoptotic signalling pathways in both normal and malignant cells. In addition he has developed new therapeutic strategies for the treatment of those diseases that are the result of defective apoptosis regulation.

    https://www.gesundheitsindustrie-bw.de/en/article/news/a-kiss-of-death-for-cells
  • Press release - 10/08/2009

    How do immune cells recognise infectious pathogens?

    Scientists of the University of Heidelberg and the German Cancer Research Centre have clarified the functional principles of an important receptor for bacterial infections: immune cells recognise bacterial and viral pathogens with a receptor known as toll-like receptor 9 (TLR9), which mediates biochemical reaction chains in order to fend off intruders. This discovery made by the Heidelberg researchers paves the way to develop new anti-infective…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-do-immune-cells-recognise-infectious-pathogens
  • Dossier - 30/07/2009 Downstream GMP production suite (Photo: Rentschler Biotechnologie)

    Downstream processing: bottleneck purification process

    The fermentation processes that are used by biopharmaceutical manufacturers have shown to lead to increasing quantities of therapeutic proteins. However this increase in turn leads to capacity bottlenecks in the subsequent purification process known as downstream processing and is associated with high costs. Downstream processing comprises up to 80 per cent of the entire production costs. Producers are increasingly recognising the present need…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/downstream-processing-bottleneck-purification-process
  • Article - 24/06/2009 The photo shows four pictures – origin-CFP, DnaA-YFP, DnaX-RFG and overlay, including three photos showing Bacillus subtilis cells under the fluorescence microscope. The bars indicate the dividing walls between the cells. The left photo shows the coupling of the origin areas with CFP; the green glow shows the location of the areas at the cell poles. The second photo shows the location of DnaA in the centre of the cells, coupled with red fluorescing YFP. The third photo shows the components of the replication machinery in yellow. The photo on the right shows an overlay of the three photos.

    The initiation of replication – only once, please

    DNA replication is a critical event in the cell division process. The genetic material must only be replicated once. So, how does a bacterial cell ensure that only one single replication occurs and that the process is not repeated several times? Microbiologists under the leadership of Prof. Dr. Peter Graumann from the Institute of Biology II in Freiburg, in cooperation with international cooperation partners from Paris, have deciphered a…

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-initiation-of-replication-only-once-please
  • Press release - 01/05/2009 08520_de.jpg

    They have the super cell

    In the Year of Science which is being celebrated in the city of Constance in 2009 the company Trenzyme located in the Constance industrial park is a prime example of science and industry working successfully hand in hand on the Nycomed campus.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/they-have-the-super-cell
  • Article - 21/04/2009 08456_de.jpg

    Two separate defence systems?

    Are the innate and the adaptive immune systems really completely independent from each other? Dr. Mathias Lucas from the University of Freiburg investigates receptor proteins that are found in the cells of both systems. It is possible that such systems might not only play a role in infections or cancer, but also in autoimmune diseases such as rheumatoid arthritis.

    https://www.gesundheitsindustrie-bw.de/en/article/news/two-separate-defence-systems
  • Article - 07/04/2009 08373_de.jpg

    Hendrik Küpper – at the service of plants and humans

    Prof. Hendrik Küpper had his first experience as a scientist in 1992 when together with his brother and a friend he participated in the German governments Jugend forscht contest. The students came first in biology in the national competition and first in both the Young Europeans Environmental Research Contest and the European Community Contest for Young Scientists. Back then Küpper was already interested in the interaction between heavy metals…

    https://www.gesundheitsindustrie-bw.de/en/article/news/hendrik-kuepper-at-the-service-of-plants-and-humans
  • Article - 30/03/2009

    More than milk and business

    Although there is very little difference between the biotechnological methods used in the dairy industry and those used in other industries nevertheless biotechnology operates differently here. Why can certain goals sometimes be reached more effectively without academic research?

    https://www.gesundheitsindustrie-bw.de/en/article/news/more-than-milk-and-business

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