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  • Press release - 07/12/2020

    One for all

    AI-based evaluation of medical imaging data usually requires a specially developed algorithm for each task. Scientists from the German Cancer Research Center (DKFZ) have now presented a new method for configuring self-learning algorithms for a large number of different imaging datasets – without the need for specialist knowledge or very significant computing power.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/one-all
  • Press release - 26/11/2020

    New mechanism of action: A small-molecule degrades a cancer-promoting protein by gluing it into filaments

    “Molecular glue degraders” are a new class of cancer drugs, which “glue” cancer growth-promoting proteins directly to the molecular machinery of a cell’s disposal system, leading to the subsequent degradation of the cancer-driving proteins and anti-tumor activity. Scientists from Heidelberg and USA have now deciphered another mechanism whereby a small molecule can degrade a cancer protein.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/new-mechanism-action-small-molecule-degrades-cancer-promoting-protein-gluing-it-filaments
  • Press release - 09/11/2020

    Making sense of what you see in biomedical images

    Sometimes an image is just an image. Sometimes it gives those who can read it correctly a deeper insight into what they can see. In many scientific disciplines, the key to extracting meaningful information from large three-dimensional images, obtained from X-ray tomography or optical microscopy, is segmentation, a tedious and time-consuming – and therefore error-prone – task if done manually.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/making-sense-what-you-see-biomedical-images
  • Press release - 15/10/2020

    Common Vulnerabilities of Coronaviruses

    International study in which Freiburg scientists are participating maps molecular targets for possible therapy for MERS, SARS-CoV1, and SARS-CoV2.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/common-vulnerabilities-coronaviruses
  • Expert interview - 13/05/2019 Telemedizin: Vitor Vieira (Inova DE) mit einem selbst entwickelten Wearable, einem T-Shirt zur verbesserten Interaktion zwischen Patienten und Kardiologen für fernkontrolliertes Monitoring

    Innovation management in the life sciences – Inova DE provides insights

    Personalized medicine, medical technology, digital health and artificial intelligence are revolutionizing diagnostics and product development. Analyses are becoming faster and more precise, and data volumes can now be networked and used effectively. The goal of improving people's quality of life is within reach, and this will also strengthen Germany’s future viability. However, not every good idea can be turned into a marketable commodity.…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/innovation-management-in-the-life-sciences-inova-de-provides-insights
  • Article - 26/04/2017 Schematic representation of a mechanism leading to the fragmentation of amyloid fibrils.

    Chaperones disassemble Parkinson’s disease-specific amyloid fibrils

    Amyloid fibrils consisting of clumped α-synuclein protein are characteristic of Parkinson's disease. Chaperones, which ensure the correct folding of newly synthesised polypeptides, can inhibit α-synuclein aggregation and, as a consequence, prevent fibrils from forming. Researchers from Heidelberg have shown that a specific combination of human molecular chaperones is able to disassemble fibrils and transform them into non-toxic α-synuclein…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/chaperones-disassemble-parkinsons-disease-specific-amyloid-fibrils
  • Article - 12/04/2017 Simone Pöschel using an ImageStream®X device

    Imaging flow cytometry – introducing a new era of imaging

    High-resolution images or quantifiable results? Up until now, researchers usually had to choose. All this has now changed thanks to a single device known as an imaging flow cytometer that combines fluorescence microscopy and flow cytometry. The new device gives new insights into complex biological phenomena in cells. It is available for research purposes at the Research Centre for Women’s Health at the University Hospital of Tübingen, which…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/imaging-flow-cytometry-introducing-a-new-era-of-imaging
  • Press release - 31/01/2017 Hoechstaufloesende-Lichtmikroskopie-ohne-Untergrund.jpg

    Background Suppression for Super-resolution Light Microscopy

    Researchers of Karlsruhe Institute of Technology (KIT) have developed a new fluorescence microscopy method: STEDD (Stimulation Emission Double Depletion) nanoscopy produces images of highest resolution with suppressed background. The new method yields an enhanced image quality, which is advantageous when analyzing three-dimensional, densely arranged subcellular structures. STEDD, a further development of the STED method, is now presented in…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/background-suppression-for-super-resolution-light-microscopy
  • Article - 11/07/2016 Photo of the members of the Department of Redox Regulation.

    Endogenous oxidants: biosensor monitoring of metabolic conditions in living organisms

    The oxidation state of the cells in our body is very important for us: if the normal balance of the distribution of endogenous oxidants is disturbed or if they attack cellular structures, cells are either unable or only partially able to fulfil their functions, and diseases develop. Dr. Tobias Dick and his team of researchers at the German Cancer Research Center (DKFZ) in Heidelberg have now developed a biosensor that facilitates real-time…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/endogenous-oxidants-biosensor-monitoring-of-metabolic-conditions-in-living-organisms
  • Company profile - 05/07/2016 Logo_final.jpg

    HS-Analysis GmbH – using digital histology to develop new drugs

    The idea of analysing tissue samples automatically sounds more of a pipe dream than anything else. However, it already happens. HS-Analysis GmbH's ability to interpret tissue samples automatically is driving new drug development a decisive step forward.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/hs-analysis-gmbh-using-digital-histology-to-develop-new-drugs
  • Article - 24/03/2016 The meeting participants are sitting on chairs, listening to the talks.

    Retrospective: Meet & Match "Optical Imaging: Future Trends in Medical Applications"

    The Meet & Match event “Optical Imaging: Future Trends in Medical Applications” – organised by BIOPRO Baden-Württemberg GmbH and the Fraunhofer Project Group for Automation in Medicine and Biotechnology (PAMB) in Mannheim on 9th March 2016 - attracted around 80 participants. Interesting lectures provided in-depth insights into future trends in optical imaging in medical applications.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/retrospective-meet-match-optical-imaging-future-trends-in-medical-applications
  • Article - 26/10/2015 Photo of Stefan Hell

    Ultrafast STED nanoscopy

    Nobel Laureate Stefan Hell and his team at the German Cancer Research Center in Heidelberg have achieved yet another milestone in super-resolved optical microscopy. The team have developed an ultrafast STED (stimulation emission depletion) nanoscope that now makes it possible to study molecular processes and transport processes in living cells in millisecond time steps.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/ultrafast-sted-nanoscopy
  • Article - 21/09/2015 Close-up of the silicon chip (purple), which is connected to the sensor board by fine gold wires.

    Venneos: technology that looks at cells differently

    The images of living cells that Venneos GmbH delivers are quite different from those captured by light microscopes. This is because the company, which was established in 2014, uses semi-conductors rather than optical lenses, thus opening up entirely new ways to analyse cells.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/venneos-technology-that-looks-at-cells-differently
  • Press release - 11/09/2015

    Venneos raises seed round of 1 million euros

    Venneos GmbH is based in Stuttgart and develops a novel imaging system for the analysis of biological cells. A consortium of business angels and family offices, along with the High-Tech Gründerfonds and Max Planck Society invest in the company to develop a market-ready product and prepare the market entry of the first product generation.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/venneos-raises-seed-round-of-1-million-euros
  • Article - 01/06/2015 Prof. Dr. Elke Deuerling and Dr. Martin Gamerdinger in the laboratory.<br /> <br />

    A protein complex that maintains order in the cell

    Researchers believe that the defective transport of proteins can be linked with diseases such as Alzheimer’s. Prof. Dr. Elke Deuerling and Dr. Martin Gamerdinger, molecular biologists from the University of Konstanz, have now discovered what is necessary to prevent erroneous protein transport.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/a-protein-complex-that-maintains-order-in-the-cell
  • Article - 02/03/2015 22850_de.jpg

    EU supports biophysicists from Ulm to elucidate the structure of chromatin

    Human DNA consists of three billion base pairs, which corresponds to a total length of approximately two metres. DNA must be compressed 200,000-fold in order to fit into the tiny nuclei of mammalian cells. The thread-like complex of DNA and proteins is called chromatin. Although chromatin has been widely studied, relatively little is yet known about the spatial and temporal organisation of chromatin in interphase cells.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/eu-supports-biophysicists-from-ulm-to-elucidate-the-structure-of-chromatin
  • Article - 08/12/2014 Portrait of Stefan Hell

    Stefan Hell – a Nobel Prize for a lateral thinker

    Stefan Hell was awarded the Nobel Prize in Chemistry for the development of STED fluorescence microscopy which has made it possible to obtain optical images well below the optical diffraction limit. However, Hell does not really see himself as a developer. His passion is scientific principles, the identification of how things are connected and the exploration of new, uncharted paths.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/stefan-hell-a-nobel-prize-for-a-lateral-thinker
  • Press release - 09/10/2014 22223_de.jpg

    Stefan Hell - Nobel Prize in Chemistry

    For the second time a researcher at the DKFZ has been awarded the highest distinction in science: Professor Stefan Hell, director of the Max-Planck Institute for Biophysical Chemistry in Göttingen and department head at the DKFZ, has been awarded this year´s Nobel Prize in Chemistry for his pioneering work in the field of ultra high resolution fluorescence microscopy. This follows the 2008 Nobel Prize in Medicine for Harald zur Hausen.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/stefan-hell-nobel-prize-in-chemistry
  • Dossier - 02/06/2014 13521_de.jpg

    Bioanalysis – techniques for the characterization of biological material

    Science constantly provides researchers with new challenges biologists and bioanalysts have to deal with and which come from sources as varied as the ever increasing number of resistant pathogenic bacterial strains or the famine conditions in Third-World countries. In the search for scientific truths bioanalysis is the development optimization and application of the entire range of analytical methods available. However we need to keep in mind…

    https:////www.gesundheitsindustrie-bw.de/en/article/dossier/bioanalysis-techniques-for-the-characterization-of-biological-material
  • Dossier - 28/04/2014 Researcher sitting in front of two screens, visualising a protein on the screen using a specific software.<br />

    Data mining: new opportunities for medicine and public health

    Research and healthcare activities produce huge quantities of data that need to be presented in an understandable structure. This requires computer-assisted extraction of relevant data and the use of statistical methods. This process, known as data mining, enables the discovery of patterns in large data sets. Data mining methods are of particular importance in fields that use high-throughput methods, visualisation methods and telemedical…

    https:////www.gesundheitsindustrie-bw.de/en/article/dossier/data-mining-new-opportunities-for-medicine-and-public-health
  • Article - 22/07/2013 20103_de.jpg

    Marcus Fändrich strengthens protein biochemistry at Ulm University

    After quite a long vacancy the directors post of the Institute for Pharmaceutical Biotechnology at the University of Ulm has finally been filled. Marcus Fändrich and his team moved into the laboratories and offices of the new life sciences building on the Oberer Eselsberg Ulm University campus in November 2012. Fändrich fills a gap in the Ulm Bioregions biopharmaceutical education activities as he will not only be teaching biochemistry…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/marcus-faendrich-strengthens-protein-biochemistry-at-ulm-university
  • Article - 31/12/2012 18995_de.jpg

    siRNA for the regeneration of tissue and nerves

    Regenerative medicine is increasingly making use of siRNA to turn off proteins that prevent the application of regenerative therapies. Researchers at the NMI in Reutlingen develop siRNA technologies that have the potential to prevent the development of fibroses, the encapsulation of implants and improve the regeneration of nerves.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/sirna-for-the-regeneration-of-tissue-and-nerves
  • Article - 29/10/2012 18508_de.jpg

    Tilman Schäffer: Biology and medicine – from the point of view of physics

    Tilman Schäffer at the University of Tübingen creates a bridge between physics, biology and medicine. His speciality is innovative microscopic detection methods such as atomic force microscopy. In addition to application, Schäffer is working on improving scanning probe microscopy instrumentation and methods.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/tilman-schaeffer-biology-and-medicine-from-the-point-of-view-of-physics
  • Article - 23/07/2012 The photo shows a group of five people standing in a row.

    The identification of stress molecules in living fish

    Fireflies use light to attract mates and hunt prey the zebrafish in Dr. Thomas Dickmeis laboratory mainly glow in situations of stress. The biologist from the Karlsruhe Institute of Technology KIT and two of his doctoral students have created a zebrafish line that can be used as a high-throughput test system for glucocorticoid hormones. Pharmaceutical companies might in future be able to use living vertebrate models i.e. zebrafish to test new…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/the-identification-of-stress-molecules-in-living-fish
  • Press release - 14/03/2012 16661_de.jpg

    How a natural antibiotic found in sweat affects microorganisms

    The skin creates a barrier between the body and its environment. Natural antibiotics that can kill potential pathogens such as bacteria or fungi represent an additional level of protection by the immune system. Dermcidin one such antibiotic produced in human sweat glands is active against a number of microorganisms on the skin. A team of scientists from the University Hospital Tübingen and the Max Planck Institute for Developmental Biology were…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/how-a-natural-antibiotic-found-in-sweat-affects-microorganisms

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