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  • Article - 04/11/2008

    "Marathon mouse" runs with a gene defect

    Researchers at the University Hospital of Heidelberg are investigating the effect of signalling substances on muscle development. If mice are missing a gene for a certain muscle protein they become marathon runners.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/marathon-mouse-runs-with-a-gene-defect
  • Article - 15/12/2014 Schematic showing how cardiac muscle cells are prepared, and how cell nuclei and the genetic material are isolated.

    Heart muscle cell 1.0 and 2.0 – two epigenetic programmes in one cell

    All the cells in an organism have to adapt to changing requirements as they develop and grow - including muscle cells in the heart. Crucial to this process are the cells’ growth in size and epigenetic factors that play a role in modulating the expression of various genes. The role of epigenetics in cancer development has been the focus of research for quite some time. The question is, what role do epigenetic factors play in the development of the…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/heart-muscle-cell-1-0-and-2-0-two-epigenetic-programmes-in-one-cell
  • Article - 29/03/2016 Photo of five zebrafish.

    The zebrafish can mend its own heart

    In adults, cells such as nerve or cardiac muscle cells have lost the ability to regenerate. This is why myocardial infarction is so dangerous – damaged cardiac muscle cells do not grow back and scar tissue forms in their place. Prof. Dr. Gilbert Weidinger and an international team of researchers have deciphered a mechanism responsible for the regeneration of the zebrafish heart.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/the-zebrafish-can-mend-its-own-heart
  • Dossier - 01/07/2013 Patch clamping: A glass pipette is used to suck in a membrane patch of a cell. (Diagram: NMI)

    Electrophysiology – from cardiac pacemakers to drug discovery

    Electrochemical reactions are involved in many processes in the human organism. Electrophysiology is the study of the central processes of electrical and chemical interaction and communication between neurons and muscle cells, including the transmission and processing of signals in the nerves and the subsequent contraction of the muscles. For example, electrophysiology studies examine the rhythm which which our heart pumps blood through the…

    https:////www.gesundheitsindustrie-bw.de/en/article/dossier/electrophysiology-from-cardiac-pacemakers-to-drug-discovery
  • Press release - 26/03/2010 10875_de.jpg

    Restarting the muscular engine – Research Prize awarded to two medical practitioners from Ulm and Heidelberg

    Dr. Karin Jurkat-Rott, associate professor at the Institute of Applied Physiology at the University of Ulm, and Dr. Marc-André Weber, associate professor and chief physician in the Department of Radiology at the Heidelberg University Hospital, were awarded the Eva Luise Köhler Research Prize for Rare Diseases in Berlin on 1st March 2010. The prize was awarded by Luise Köhler in the presence the German Federal President Horst Köhler, the German…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/restarting-the-muscular-engine-research-prize-awarded-to-two-medical-practitioners-from-ulm-and-heid
  • Press release - 30/03/2011 14050_de.jpg

    Scientists Find Cause of Fatal Inflammation of the Heart Muscle

    Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), jointly with colleagues in the United States, have found out that inflammations of the heart muscle are caused by attacks of a specific type of immune cells. These immune cells attack the body’s own tissue because during their maturation they did not have the chance to develop tolerance against a protein that is only found in the heart muscle.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/scientists-find-cause-of-fatal-inflammation-of-the-heart-muscle
  • Press release - 13/11/2009 10092_de.jpg

    New genetic cause of cardiac insufficiency discovered

    The heart needs to pump approximately 250 million litres of blood through the body during a person’s lifetime. In order to do this effectively, the cardiac muscle fibres need to be extremely resilient. A team led by Dr. Wolfgang Rottbauer, assistant medical director of the Department of Internal Medicine III at the University Hospital of Heidelberg, has discovered a protein component that is responsible for the stability of the smallest muscle…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/new-genetic-cause-of-cardiac-insufficiency-discovered
  • Article - 17/04/2010 11094_de.jpg

    Sounding out human motion

    Although standing upright and moving forward may appear to be simple, they are in fact complex activities that are not yet understood in detail. Even less is known about how we hop, run and jump. Researchers at the Stuttgart-based Institute of Sport and Movement Science are looking into the ways the musculoskeletal system interacts to create movements as well as studying the effect of disorders. Computer simulation is one of the principal tools…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/sounding-out-human-motion
  • Article - 18/04/2008

    Better bypass with gene therapy?

    Almost half of the veins transplanted to restore blood flow in the heart become clogged again within ten years after surgery. Gene therapy pre-treatment of the vein fragments that prevents the muscle cells from entering the vascular wall might decrease the risk of this happening.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/better-bypass-with-gene-therapy
  • Dossier - 12/04/2010 11107_de.jpg

    Biomechanics – a broad field

    Biomechanics is a combination of the life sciences and the engineering sciences. Based on their knowledge and understanding of mechanics and the development of complex mathematical models and computer simulations engineers mathematicians and computer specialists help scientists gain new insights and give medical specialists access to new therapeutic options. In many cases such as in the development of implants or in sports medicine engineers…

    https:////www.gesundheitsindustrie-bw.de/en/article/dossier/biomechanics-a-broad-field
  • Article - 20/12/2007

    Viruses are the major cause of myocardial diseases

    About 500000 people in Germany suffer from dilatative cardiomyopathy DCM. Viral infections are the major cause of this myocardial disease. Its molecular and cellular mechanisms are being investigated in a transregional SFB project at the University of Tübingen.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/viruses-are-the-major-cause-of-myocardial-diseases
  • Article - 08/09/2008

    Research increases hope

    Duchenne muscular dystrophy DMD is a severe disease affecting boys characterised by rapid progression of muscle degeneration so that boys as young as 10 to 12 years of age have to use a wheelchair and leading to death in young men. In Germany about 2500 children and young adults suffer from DMD.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/research-increases-hope
  • Press release - 06/06/2008

    Collaborative research centre on cardiac diseases to receive further funding

    The German Research Foundation will continue to fund the Transregional Collaborative Research Centre Inflammatory Cardiomyopathy - Molecular Pathogenesis and Therapy for another four years with a total of 10 million euros. The Department of Cardiology of the University Hospital of Tübingen will also become part of the SFB.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/collaborative-research-centre-on-cardiac-diseases-to-receive-further-funding
  • Article - 12/04/2010 The photo shows a person on her back and strapped into an apparatus. The person's feet touch a disc.<br />

    Why do weightless bodies have to vibrate?

    “It is a totally new feeling,” said Ramona Ritzmann from the University of Freiburg referring to the feeling of weightlessness she experienced during her experiments on board the Airbus 300. Something that can trigger amazing sensations over a short period of time, can have seriously negative consequences for astronauts. Prolonged stays aboard the International Space Station ISS can lead to muscle degeneration. Along with her colleagues Andreas…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/why-do-weightless-bodies-have-to-vibrate
  • Article - 31/10/2008

    Using the power of thought to control an artificial hand

    During his doctorate Dr Rüdiger Rupp from the University of Heidelberg developed neuroprostheses that can be controlled with weak muscle tension or even with thought power. Rupp was awarded the Konrad Biesalski Prize of 5000.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/using-the-power-of-thought-to-control-an-artificial-hand
  • Article - 18/10/2008

    Protein protects the heart from cardiac hypertrophy

    The scientist Dr. Derk Frank from Heidelberg has discovered that calsarcin 1 protects the heart against pathological alterations caused by overstraining. Frank was awarded the 2008 Gotthard Schettler Prize for Cardiovascular Research.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/protein-protects-the-heart-from-cardiac-hypertrophy
  • Article - 14/04/2008

    Molecular cell recognition - putting the brain in order

    The neurogeneticists in the group of Professor Karl-Friedrich Fischbach at the University of Freiburg are investigating how the complex optical areas of the brain are organised. They found that proteins form a functional unit.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/molecular-cell-recognition-putting-the-brain-in-order
  • Press release - 20/02/2008

    ZRM and Naturin develop innovative biomembranes

    The Centre for Regenerative Biology and Medicine ZRM in Tübingen has joined forces with Naturin GmbH based in Weinheim. The partners plan to develop new carrier materials on the basis of collagen which improve cell cultures and medical implants.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/zrm-and-naturin-develop-innovative-biomembranes
  • Article - 18/03/2013 Electron microscope image of small S100A6 aggregates that form larger fibrils.

    Protein depositions in the brain promote the development of amyotrophic lateral sclerosis (ALS)

    Being aware of ones own physical degradation as intellect and cognition remain completely intact this is what the disease amyotrophic lateral sclerosis ALS also known as Lou Gehrigs disease means to sufferers. The disease is currently not curable as far too little is known as yet about its causes. However basic research is making progress and providing increasing insights into the causes of ALS. Dr. Günter Fritz and his colleagues from the…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/protein-depositions-in-the-brain-promote-the-development-of-amyotrophic-lateral-sclerosis-als
  • Article - 26/10/2011 15720_de.jpg

    Simple nerve cells regulate swimming depth of marine plankton

    Scientists of the Max Planck Institute for Developmental Biology in Tübingen Germany have identified some signaling substances in the nervous system of larvae of the marine annelid Platynereis regulating the swimming depth. These substances influence the ciliary beating and thus hold the larvae in the preferred water depth. The scientists discovered a very simple circuitry of nerve cells underlying this regulation reflecting an early evolutionary…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/simple-nerve-cells-regulate-swimming-depth-of-marine-plankton
  • Press release - 18/03/2013 19373_de.jpg

    Med Cell Europe AG: medicine from a patient’s own adipose tissue

    Med Cell Europe AG, which is headquartered in Münchwilen, Switzerland, and a member of the BioLAGO bioregion, is the only private stem cell bank in Europe that isolates adult stem cells from customers’ adipose tissue. The biotech company, which was founded in 2010, is also active in research. The focus, amongst other things, is on the transformation of stem cells into insulin-producing cells and cytotoxicity tests to explore potential damage to…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/med-cell-europe-ag-medicine-from-a-patient-s-own-adipose-tissue
  • Article - 30/08/2008

    Helpful toxins

    Sometimes a few nanogrammes of toxin are all that is needed to kill someone. Prof. Dr. Dr. Klaus Aktories from the Institute of Experimental and Clinical Pharmacy at the University of Freiburg is investigating why some bacterial toxins are so extremely toxic. Together with his team of researchers Aktories has identified the molecular mechanism of action of Clostridium difficile toxins.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/helpful-toxins
  • Article - 16/05/2011 14292_de.jpg

    Oliver Röhrle and the biomechanics of the musculo-skeletal system

    Dr. Oliver Röhrle contributes to the excellent standards in the field of biomechanics at the University of Stuttgart. He has held one of the popular junior professorships in the Simulation Technology (SimTech) cluster of excellence since 2008 and has recently received a research prize for his work on the biomechanics of the musculo-skeletal system.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/oliver-roehrle-and-the-biomechanics-of-the-musculo-skeletal-system
  • Article - 18/03/2010 Restructering processes of epithelial cells occuring as the result of respiratory diseases. Model.<br />

    Boehringer Ingelheim researchers to focus on inflammation

    Boehringer Ingelheim is hoping to find ways to use anti-inflammatory mechanisms of action to improve the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. Clinical studies will show what kind of improvements patients can expect from the substances, which are currently at different stages of development. Drugs to widen the bronchia, marketed by Boehringer Ingelheim, will in the medium term become…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/boehringer-ingelheim-researchers-to-focus-on-inflammation
  • Press release - 08/01/2009 The figure shows an XY coordinate system with 5 meandering curves that extend to the lower right-hand corner (colour and labelling (from top to bottom): light blue (60 cylinders, p=47,1%), dark blue (30 cylinders, p=23,6%), green (15 cylinders, p=11,8%), red (5 cylinders, p=3,9%), yellow (1 cylinder, p=0,8%)). The curves consist of a sequence of spots (legend: Monte Carlo) and lines (legend: Maxwell). X axis: angle (°), Y axis: differential scattering cross section (m rad -1). <br /> <br />

    ILM – Light scattering of cylindrical structures

    Many biological tissues contain cylindrical microstructures, including teeth, muscles and skin. Therefore, the detailed understanding of light propagation in these structures is of great importance for biomedical optics. The transport theory is often used for the numerical calculation of light propagation in biological tissue. The ILM uses the Monte Carlo method to make these calculations.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/ilm-light-scattering-of-cylindrical-structures

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