Press release - 18/11/2021 Overcoming resistance to treatment for breast, bowel, and pancreatic cancer As cancer progresses, the tumor cells continually change, ultimately resulting in a tumor consisting of a large number of different cell clones with different characteristics. This is referred to as "tumor heterogeneity". In many cases, the cancer cells become resistant to the treatments available.https://www.gesundheitsindustrie-bw.de/en/article/press-release/overcoming-resistance-treatment-breast-bowel-and-pancreatic-cancer
Press release - 18/11/2021 Overcoming resistance to cancer treatment: bone and soft tissue tumors in adolescents as a model system Treatment resistance is a central problem in the treatment of cancer. Bone and soft tissue tumors – known as sarcomas – in adolescents and young adults often stop responding to treatment too. This is because cancer cells develop a large number of new characteristics as the disease progresses and often become resistant to drugs that were originally effective.https://www.gesundheitsindustrie-bw.de/en/article/press-release/overcoming-resistance-cancer-treatment-bone-and-soft-tissue-tumors-adolescents-model-system
Funding EU4Health- Programme Funding programme, Funded by: European Union, sb_search.searchresult.label.programSubmissionDate: 31/12/2027 https://www.gesundheitsindustrie-bw.de/en/database/funding/eu4health-programme
Funding EU4Health- Programme Funding programme, Funded by: European Union, sb_search.searchresult.label.programSubmissionDate: 31/12/2027 https://www.bio-pro.de/en/service/funding/eu4health-programme
Start-up PROSERVATION - sustainable packaging - 21/09/2021 Husk as a substitute for polystyrene: packaging materials with a good conscience Expanded polystyrene (EPS) packaging is very practical, but it is made from petroleum and is not very environmentally friendly in other ways either. Single-use plastic containers made of EPS have therefore been banned in the EU, but alternatives are also urgently needed. The Stuttgart-based start-up PROSERVATION has developed an ecological packaging material made from grain husks that could replace EPS and be just as effective.https://www.biooekonomie-bw.de/en/articles/news/husk-substitute-polystyrene-packaging-materials-good-conscience
Press release - 21/09/2021 Antibiotic levels measurable in breath for first time A team of engineers and biotechnologists at the University of Freiburg has for the first time shown in mammals that the concentration of antibiotics in the body can be determined using breath samples. The breath measurements also corresponded to the antibiotic concentrations in the blood. The team’s biosensor – a multiplex chip – will in future enable personalized dosing of medicines against infectious diseases on-site.https://www.gesundheitsindustrie-bw.de/en/article/press-release/antibiotic-levels-measurable-breath-first-time
Press release - 02/09/2021 Award-winning science: Cancer-promoting metabolic pathways as targets of new therapies Christiane Opitz, scientist at the German Cancer Research Center, is being awarded this year's Ita Askonas Prize of the European Federation of Immunological Societies. Opitz has discovered how tumor cells use certain metabolites to protect themselves against the immune system. Her research findings may provide important clues for the development of new therapeutic concepts.https://www.gesundheitsindustrie-bw.de/en/article/press-release/award-winning-science-cancer-promoting-metabolic-pathways-targets-new-therapies
Press release - 01/09/2021 Watch out, mold: Fraunhofer solution simulates bamboo’s response to moisture when used in construction As a rapidly growing renewable raw material, bamboo is an ideal substitute for wood. However, bamboo’s susceptibility to mold in damp conditions poses a problem. Researchers at Fraunhofer have now analyzed bamboo’s response to moisture under specific climatic conditions. By using simulation software, building owners can plan and implement measures to prevent the growth of mold.https://www.biooekonomie-bw.de/en/articles/pm/watch-out-mold-fraunhofer-solution-simulates-bamboos-response-moisture-when-used-construction
Press release - 25/05/2021 From harmless skin bacteria to dreaded pathogens The bacterium Staphylococcus epidermidisis primarily a harmless microbe found on the skin and in the noses of humans. Yet some strains of this species can cause infections – in catheters, artificial joints, heart valves, and in the bloodstream – which are difficult to treat. These bacteria are often resistant to a particularly effective antibiotic, methicillin, and are among the most feared germs in hospitals.https://www.gesundheitsindustrie-bw.de/en/article/press-release/harmless-skin-bacteria-dreaded-pathogens
Press release - 23/04/2021 The Amazing Field of Science: Bioeconomy to End the Ecological Crisis Population growth and the increasing standard of living make our society face big ecological challenges: Climate change, littering of the seas, dwindling agricultural areas, resource scarcity. Bioeconomy aims at replacing fossil by regenerative resources and at using advanced and sustainable technologies based on biological knowledge and principles.https://www.biooekonomie-bw.de/en/articles/pm/amazing-field-science-bioeconomy-end-ecological-crisis
Article - 17/03/2021 Epigenetic switches in bacteria as biosensors The analysis of pathogen biomarkers and biomarkers for the diagnosis of diseases can be crucial for health. However, the detection of pathogens and diseases depends on a sensitive and reliable method that delivers rapid results. Biosensors have such properties. Researchers at the Institute of Biochemistry and Technical Biochemistry (IBTB) at Stuttgart University have constructed an epigenetic circuit composed of plasmids that might make it…https://www.gesundheitsindustrie-bw.de/en/article/news/epigenetic-switches-bacteria-biosensors
Press release - 18/01/2021 How a protein variant could explain resistance to sleeping sickness drug A specific variant of the surface protein VSG of African trypanosomes, the causative agents of sleeping sickness, is associated with resistance to the important drug Suramin. Scientists at the German Cancer Research Center have now been able to find a possible explanation for the formation of resistance based on the crystal structure of this protein variant.https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-protein-variant-could-explain-resistance-sleeping-sickness-drug
Infection control - 07/01/2021 Gene accordions as potential markers for pathogenic properties Bacteria must react to changes in the environment in order to survive. This is partly done by adapting genetic material, for example by multiplying and shortening individual genome segments. The research group led by Dr. Simon Heilbronner from the Interfaculty Institute of Microbiology and Infection Medicine at the University of Tübingen has shown that these so-called gene accordions are frequently found in the bacterium Staphylococcus aureus.https://www.gesundheitsindustrie-bw.de/en/article/news/gene-accordions-potential-markers-pathogenic-properties
Lab-on-a-chip - 11/11/2020 Microfluidic platform for the best possible cancer therapy Every tumour and every patient is different, and there are individual reactions to drugs as well as the problem of resistance. Patient-specific cancer treatments require innovative and cost-effective approaches. The TheraMe! consortium has developed a novel instrument: a combination of microfluidic experiments and mathematical modelling for use in cancer precision medicine to prevent incorrect therapy options.https://www.gesundheitsindustrie-bw.de/en/article/news/microfluidic-platform-best-possible-cancer-therapy
Phosphorus recovery from sewage sludge - 21/10/2020 Bacteria help to recycle phosphorus Biotechnology for the bioeconomy: in something known as the P-bac process, sulphur bacteria extract phosphorus from sewage sludge ash. Phosphorus is one of the key building blocks of life and an essential nutrient for plant growth. When there is not enough phosphorus in the soil, farmers apply it via organic or mineral fertilisers.https://www.biooekonomie-bw.de/en/articles/news/bacteria-help-recycle-phosphorus
Atriva Therapeutics - 21/10/2020 COVID-19 pioneer drug in Phase II clinical trial - with double the power The effective treatment of people with severe COVID-19 is a major goal during the corona pandemic. ATR-002, an oral small molecule that targets RNA viruses such as influenza virus and SARS-CoV-2, has a dual effect: it impairs viral propagation and also has an immunomodulatory effect. And what’s more, due to its unique cellular mechanism of action, the efficacy of Atrivia Therapeutics’ drug candidate is not reduced by virus mutations and…https://www.gesundheitsindustrie-bw.de/en/article/news/covid-19-pioneer-drug-phase-ii-clinical-trial-double-power
Qualitative soil fertiliser - 10/07/2020 How natural cycles can be closed with wood ash Recycled material instead of waste: wood ash is good for soil and plants - if the quality is right. The German Federal Quality Association for Food Ash ensures reliable wood ash standards with its certifications. The RAL-Dünger label for fertilisers provides the necessary certification for natural wood ashes to be used in the circular economy.https://www.biooekonomie-bw.de/en/articles/news/how-natural-cycles-can-be-closed-wood-ash
Article - 20/01/2020 Brain tumour patients could benefit from heavy ion therapy Glioblastoma is a malignant brain tumour. It does not respond anywhere near as well to conventional forms of therapy than other tumours because it contains particularly resistant cancer cells. Scientists at the Heidelberg Ion Beam Therapy Center (HIT) at Heidelberg University Hospital and the German Cancer Research Center have shown that heavy ion therapy is effective against these cells.https://www.gesundheitsindustrie-bw.de/en/article/news/Brain-tumour-patients-could-benefit-from-heavy-ion-therapy
Dossier - 06/12/2019 Microbiome: human health is closely connected with our microbial communities People have 1.3 times more microorganisms than body cells. This microbial community influences how we digest our food, how active our immune system is, as well as whether we tend to be more anxious or curious. A number of diseases have also been shown to be associated with a disturbed microbiome. Researchers still have a long way to go before the knowledge acquired can be used for developing therapies.https://www.gesundheitsindustrie-bw.de/en/article/dossier/microbiome-human-health-closely-connected-with-microbial-communities
CRISPR/Cas9 and genetic engineering laws - 27/11/2019 Transgene-free plant breeding using genome editing Plant geneticists from Tübingen have used genome deletion to breed a variety of tomato that is resistant to powdery mildew. The CRISPR/Cas9 technology that they used enabled them to achieve this in a relatively short period of time. They also demonstrated beyond any doubt that the new tomato variety contains no foreign DNA and is indistinguishable from naturally occurring deletion mutants.https://www.biooekonomie-bw.de/en/articles/news/transgene-free-plant-breeding-using-genome-editing
New edition - 24/05/2019 Tumour metastasis Cancer is usually not curable when metastases have formed in the body. Metastases are often resistant to drugs that have successfully eliminated the primary tumour. The basic features of the complex process of metastasis are now known, but many details still remain elusive. Intensive research activities are focusing on new therapeutic concepts aimed at developing effective anti-metastatic therapies.https://www.gesundheitsindustrie-bw.de/en/article/dossier/tumour-metastasis
Article - 16/04/2019 Tumour monitoring using liquid biopsy Liquid biopsy, the analysis of cancer biomarkers and circulating tumour cells in body fluids such as blood, is revolutionising the diagnosis and monitoring of cancer. It has also been possible to expand circulating tumour cells from the blood under laboratory conditions. It is expected that in the future, liquid biopsy will be able to precisely characterise tumour cells at every stage of a cancer.https://www.gesundheitsindustrie-bw.de/en/article/news/tumour-monitoring-using-liquid-biopsy
Article - 02/04/2019 Simple sugar could soon compete with glyphosate For many decades, glyphosate has been a common component of agricultural pesticides worldwide, although it is a controversial herbicide that may be harmful. The good news is that a more sustainable alternative is now in sight: researchers from the University of Tübingen have discovered a sugar molecule called 7-deoxy-sedoheptulose (7dSh) which inhibits the growth of plants and microorganisms, but appears to be completely harmless to human cells.https://www.biooekonomie-bw.de/en/articles/news/simple-sugar-could-soon-compete-with-glyphosate
Article - 24/01/2019 Scientists to combat antibiotic-resistant bacteria in wastewater In Germany, around 1,500 tonnes of antibiotics per year are administered to humans and animals. As a result, more and more bacteria are developing resistance to common antibiotics. As part of HyReKA, a cooperative project funded by the BMBF, scientists led by Professor Thomas Schwartz from the KIT are investigating how antibiotic-resistant pathogens spread and how they can be prevented from doing so.https://www.gesundheitsindustrie-bw.de/en/article/news/scientists-to-combat-antibiotic-resistant-bacteria-in-wastewater
Article - 24/01/2019 Scientists to combat antibiotic-resistant bacteria in wastewater In Germany, around 1,500 tonnes of antibiotics per year are administered to humans and animals. As a result, more and more bacteria are developing resistance to common antibiotics. As part of HyReKA, a cooperative project funded by the BMBF, scientists led by Professor Thomas Schwartz from the KIT are investigating how antibiotic-resistant pathogens spread and how they can be prevented from doing so.https://www.biooekonomie-bw.de/en/articles/news/scientists-to-combat-antibiotic-resistant-bacteria-in-wastewater