Article - 30/04/2011 The DKFZ-ZMBH Alliance The strategic alliance between the cell and tumour biology research priority at the German Cancer Research Center and the Center for Molecular Biology at Universität Heidelberg has led to the development of one of the largest centres of basic biomedical research in Germany. The top international profile of this interdisciplinary institution located at the interface between molecular and cellular biology tumour biology and biomedicine is reflected…https://www.gesundheitsindustrie-bw.de/en/article/news/the-dkfz-zmbh-alliance
Press release - 11/11/2009 Hematopoietic stem cell treatment with a new gene therapy vector: A first success treating a brain disease Two children with adrenoleukodystrophy (ALD), a fatal brain disease, have been successfully treated with a new gene therapy vector. Two years after treatment, the disease evolution has been stopped, and no adverse effect of the gene therapy has been observed so far. The results of this clinical trial conducted by Drs Nathalie Cartier and Patrick Aubourg (Inserm, France) in collaboration with European partners have just been published in Science…https://www.gesundheitsindustrie-bw.de/en/article/press-release/hematopoietic-stem-cell-treatment-with-a-new-gene-therapy-vector-a-first-success-treating-a-brain-di
Article - 24/03/2008 Successful cooperation between science and industry At the recent Science meets Business Day four tandem teams of the German BioValley Platform presented their projects. These will be introduced in two articles. The first article focuses on natural substances with a pharmaceutical potential.https://www.gesundheitsindustrie-bw.de/en/article/news/successful-cooperation-between-science-and-industry
Press release - 01/08/2012 Combination of businesses of SYGNIS and GENETRIX’ subsidiary X-Pol proposed SYGNIS Pharma AG and GENETRIX announced today, that the biotechnology companies SYGNIS and GENETRIX have signed a binding Term Sheet under which the companies propose to combine the GENETRIX’ DNA sequencing subsidiary X-Pol Biotech and SYGNIS. Goal is to develop and market X-Pol Biotech, S.L.’s DNA sequencing technologies and products.https://www.gesundheitsindustrie-bw.de/en/article/press-release/combination-of-businesses-of-sygnis-and-genetrix-subsidiary-x-pol-proposed
Press release - 23/11/2009 GATC Biotech soon opens sequencing laboratory in London GATC Biotech Europes leading sequencing service provider for industrial and academic research announces that it will open a sequencing laboratory in London to provide scientists in UK and Ireland with single sample sequencing services. The GATC London Laboratory will be situated in the London BioScience Innovation Centre LBIC and will start operations on January 4 2010. https://www.gesundheitsindustrie-bw.de/en/article/press-release/gatc-biotech-soon-opens-sequencing-laboratory-in-london
Press release - 01/10/2008 Virtual database screening saves time and money In order to be able to manage the growing amount of information in the life sciences the international research community has developed numerous electronic databases over the last few years. Supported by sophisticated software programmes the stored information can now be analysed effectively. In parallel with work-intensive screening methods which involve many laboratory experiments scientists are increasingly relying on computer-based methods. https://www.gesundheitsindustrie-bw.de/en/article/press-release/virtual-database-screening-saves-time-and-money
Press release - 26/03/2009 Sygnis Pharma AG increases capital SYGNIS Pharma AG reported its financial results for the first nine months of the fiscal year 20082009. The company improved its cash position significantly as a result of a successful capital increase. Following the capital increase the stake of dievini Hopp BioTech in SYGNIS Pharma AG increased to approximately 44.90 of the total share capital. The preparations for the phase II efficacy trial of its lead candidate AX200 in acute ischemic stroke…https://www.gesundheitsindustrie-bw.de/en/article/press-release/sygnis-pharma-ag-increases-capital
Press release - 02/11/2020 Juvenile myelomonocytic leukemia: International classification model allows for customized treatment Juvenile myelomonocytic leukemia (JMML) is a rare blood cancer of early childhood. Previous research activities have shown that JMML patients can be divided into three groups based on certain genetic markers, DNA methylation. Depending on the subgroup, statements can be made about the course of the disease. https://www.gesundheitsindustrie-bw.de/en/article/press-release/juvenile-myelomonocytic-leukemia-international-classification-model-allows-customized-treatment
Press release - 18/10/2021 More precise characterization of brain tumors improves diagnosis and therapy An international study with about 3000 patients confirms the validity of a new classification system for meningiomas. It combines tissue characteristics (histology) with molecular analyses and thus improves therapy planning.https://www.gesundheitsindustrie-bw.de/en/article/press-release/more-precise-characterization-brain-tumors-improves-diagnosis-and-therapy
Article - 06/08/2009 PEPperPRINT wins award for its peptide chips PEPperPRINT GmbH, a spin-off of the German Cancer Research Centre, has won the Science4Life Venture Cup, a German start-up contest that comes with the most prize money. The Heidelberg-based start-up company was previously awarded the renowned research prize by the German Stifterverband and was chosen as a “Landmark in the Land of Ideas” competition run by the German government in 2009.https://www.gesundheitsindustrie-bw.de/en/article/news/pepperprint-wins-award-for-its-peptide-chips
Article - 12/07/2010 Vesicular transport in cells – from analysis to biogenesis COPI vesicles, one of the three major types of intracellular transport vesicles, are an excellent example of how the molecular analysis of individual vesicle components can lead to an understanding of the biogenesis and transport mechanisms of membrane vesicles as a whole. The research carried out by Dr. Felix T. Wieland’s team at the University of Heidelberg has made a decisive contribution to such detailed insights.https://www.gesundheitsindustrie-bw.de/en/article/news/vesicular-transport-in-cells-from-analysis-to-biogenesis
Article - 20/02/2012 "1KITE" project to unravel the evolution of insects The large international “1K Insect Transcriptome Evolution” research project aims to construct a robust phylogenetic tree of insects, which is the most species-rich group of organisms. The project aims to study the transcriptomes of 1000 (1K) insect species. The Heidelberg-based Institute for Theoretical Studies provides the software for producing the phylogenetic trees.https://www.gesundheitsindustrie-bw.de/en/article/news/1kite-project-to-unravel-the-evolution-of-insects
Article - 02/05/2016 Hepatitis C: a new starting point for vaccine development With approximately 150,000 infected people in Germany, hepatitis C is a common disease for which therapies, but no vaccine, are available. Dr. Tobias Böttler from the Freiburg University Medical Center and his team are exploring the body’s immune response to the hepatitis C virus (HCV) and have found valuable information that could be used for vaccine development.https://www.gesundheitsindustrie-bw.de/en/article/news/hepatitis-c-a-new-starting-point-for-vaccine-development
Article - 19/07/2016 Licence to kill – the enormous potential of CAR T cells With 6 million euros of EU funding, the CARAT project aims to optimise a technology called CAR T that is used to equip T cells with antibody fragments and specifically direct them to destroy cancer cells. The CARAT consortium comprises a multinational team of experts from the Institute for Cell- and Gene Therapy at the Freiburg University Medical Center led by Prof. Dr. Toni Cathomen and seven partner institutions. Cathomen’s team is developing…https://www.gesundheitsindustrie-bw.de/en/article/news/licence-to-kill-the-enormous-potential-of-car-t-cells
Press release - 17/11/2009 iGEM team Freiburg: a standing order for gold medals The Bioware team from Freiburg, an important part of the bioss cluster of excellence, has once again achieved resounding success: one gold medal and two special prizes at the iGEM competition (international Genetically Engineered Machine), the largest event for up-and-coming scientists focusing on synthetic biology. It was the turn of the research group heads, junior professor Dr. Kristian Müller and Dr. Katja Arndt, to participate in the…https://www.gesundheitsindustrie-bw.de/en/article/press-release/igem-team-freiburg-a-standing-order-for-gold-medals
Article - 12/03/2012 Q-bios provides client-specific biotechnology services Q-bios GmbH, a spin-off from the Mannheim University of Applied Sciences, is a biotechnology company that provides services related to the production and purification of diagnostic and therapeutic proteins as well as the development and amplification of suitable cell lines. The company offers its services, which are based on state-of-the-art technologies, to clients from the biotechnology, diagnostic and pharmaceutical industries.https://www.gesundheitsindustrie-bw.de/en/article/news/q-bios-provides-client-specific-biotechnology-services
Article - 23/07/2012 Inhospitable niches are a rich source of extremozymes At first sight nothing much seems to grow in either the Namib desert or the Antarctic. However a closer inspection of the ground a few centimetres below the surface reveals an enormous diversity of organisms. Industry is well aware of this rich source of microorganisms that have something to offer on the molecular level as well as for use in technical applications. So-called extremozymes have long been popular ingredients in cosmetics detergents…https://www.gesundheitsindustrie-bw.de/en/article/news/inhospitable-niches-are-a-rich-source-of-extremozymes
Article - 16/12/2013 An RNA switch for protein mutations RNA is a family of biological molecules with multiple roles, including the transmission of information and the catalysis of chemical reactions in a similar way to enzyme action. Ribozymes (ribonucleic acid enzymes) of this kind function for example within the ribosome where they link amino acids during protein synthesis. Professor Jörg Hartig from the University of Konstanz has developed a new ribozyme-based method that enables him to control the…https://www.gesundheitsindustrie-bw.de/en/article/news/an-rna-switch-for-protein-mutations
Article - 12/09/2011 Claudia Stürmer: the growth and regeneration of nerve fibres Axons are the long, slender projections of nerve cells whose growth is governed by the intrinsic properties of neurons as well as by growth-promoting and growth-inhibiting molecules present in the neurons’ environment. In fish, the injured axons of the central nervous systems are able to regenerate. This is not the case in mammals, and therefore humans. A group of researchers led by Prof. Dr. Claudia Stürmer at the University of Konstanz is…https://www.gesundheitsindustrie-bw.de/en/article/news/claudia-stuermer-the-growth-and-regeneration-of-nerve-fibres
Article - 29/07/2013 Genetic fingerprinting - a useful method in fruit production Genetic fingerprinting is a well-known technique used for paternity testing and in forensic science. However, the technique is also used in the field of agriculture. Molecular genetics makes it possible to develop and apply new research and breeding methods to the field of fruit production in order to improve production and quality standards. Dr. Haibo Xuan from the Competence Centre for Fruit Production (KOB) at Lake Constance has been working…https://www.gesundheitsindustrie-bw.de/en/article/news/genetic-fingerprinting-a-useful-method-in-fruit-production
Article - 12/01/2011 How milk, cheese, yoghurt and curd cheese can be kept free from “genetic engineering” Bacteriophages introduce their DNA into bacteria where they quickly reproduce and eventually destroy the host organism. Phages are omnipresent in nature and some can be dangerous for humans. They also represent a huge contamination risk in the production of fermented food. Canadian researchers Lvesque et al. 2005 estimate that phages cause around 10 per cent of all production losses in the diary industry where they infest bacteria such as…https://www.gesundheitsindustrie-bw.de/en/article/news/how-milk-cheese-yoghurt-and-curd-cheese-can-be-kept-free-from-genetic-engineering
Article - 12/07/2010 Twelve in one fell swoop – New type 2 diabetes genes An international team of scientists working on the largest diabetes study to date have found 12 new diabetes genes in around 140000 Europeans. One of the authors the endocrinologist Bernhard Böhm from Ulm considers the findings to be a breakthrough in the research and treatment of type 2 diabetes. https://www.gesundheitsindustrie-bw.de/en/article/news/twelve-in-one-fell-swoop-new-type-2-diabetes-genes
Dossier - 06/03/2018 Big data - the big promise of the new digitised world Big data is a widely used buzzword in today's information era. The use of big data in the digital world presents both an opportunity and a risk. Mass data is now used and analysed in almost all areas of life. Even the healthcare sector is undergoing extensive digitisation. https://www.gesundheitsindustrie-bw.de/en/article/dossier/big-data-the-big-promise-of-the-new-digitised-world
Article - 05/03/2012 Processing of olfactory cues in the brain The question as to how the brain produces useful information from the electrical stimuli coming from the sensory organs is a key issue in the neurosciences. Researchers from Heidelberg are investigating how mice discriminate odours and have shown that complex behaviour emerges from the properties of cells and molecules. Using highly specific genetic manipulations for their experiments, the researchers have been able to show that inhibitory…https://www.gesundheitsindustrie-bw.de/en/article/news/processing-of-olfactory-cues-in-the-brain
Press release - 01/02/2012 Defects in the packaging of genetic material in malignant brain tumors Glioblastomas are regarded as particularly aggressive brain tumors. In children with glioblastoma, Heidelberg scientists have now discovered genetic alterations that affect the function of DNA packaging proteins known as histones. In a cell, histones serve as coils around which the DNA wraps. At the same time, histones regulate gene activity. Mutations in histone genes have never before been tied to a disease. The group comprising scientists of…https://www.gesundheitsindustrie-bw.de/en/article/press-release/defects-in-the-packaging-of-genetic-material-in-malignant-brain-tumors