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  • New edition - 24/05/2019 Magnetic resonance image of brain metastases.

    Tumour metastasis

    Cancer is usually not curable when metastases have formed in the body. Metastases are often resistant to drugs that have successfully eliminated the primary tumour. The basic features of the complex process of metastasis are now known, but many details still remain elusive. Intensive research activities are focusing on new therapeutic concepts aimed at developing effective anti-metastatic therapies.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/tumour-metastasis
  • Expert interview - 13/05/2019 Telemedizin: Vitor Vieira (Inova DE) mit einem selbst entwickelten Wearable, einem T-Shirt zur verbesserten Interaktion zwischen Patienten und Kardiologen für fernkontrolliertes Monitoring

    Innovation management in the life sciences – Inova DE provides insights

    Personalized medicine, medical technology, digital health and artificial intelligence are revolutionizing diagnostics and product development. Analyses are becoming faster and more precise, and data volumes can now be networked and used effectively. The goal of improving people's quality of life is within reach, and this will also strengthen Germany’s future viability. However, not every good idea can be turned into a marketable commodity.…

    https://www.gesundheitsindustrie-bw.de/en/article/news/innovation-management-in-the-life-sciences-inova-de-provides-insights
  • Article - 23/04/2019 D50_5948_b.jpg

    How can care infrastructures benefit from digitization?

    The pilot project NeCTra (Networking - Care - Transparency) investigates how care processes within an urban social environment can be improved by using digital technologies. The goal is to bring together all partners and institutions in real time so that people in need of care and those seeking advice receive appropriate support more quickly.

    https://www.gesundheitsindustrie-bw.de/en/article/news/how-can-care-infrastructures-benefit-from-digitization
  • Article - 16/04/2019 20190218_Foto_Labor_Quelle_UniversitNatsklinikum_Heidelberg.jpg

    Tumour monitoring using liquid biopsy

    Liquid biopsy, the analysis of cancer biomarkers and circulating tumour cells in body fluids such as blood, is revolutionising the diagnosis and monitoring of cancer. It has also been possible to expand circulating tumour cells from the blood under laboratory conditions. It is expected that in the future, liquid biopsy will be able to precisely characterise tumour cells at every stage of a cancer.

    https://www.gesundheitsindustrie-bw.de/en/article/news/tumour-monitoring-using-liquid-biopsy
  • Expert interview on NTDs – part 1 - 11/04/2019 Carsten_Koehler_Profilbild_Tropenkrankheiten_Tuebingen.jpg

    Neglected tropical diseases – Carsten Köhler: impulses from Baden-Württemberg

    More than one billion people worldwide suffer from neglected tropical diseases (NTDs). NTDs are mostly poverty-related infectious diseases that prevail in tropical countries due to lack of research and measures to detect, prevent and control them. Dr. Dr. Carsten Köhler reports on the political, economic and scientific contributions Germany and Baden-Württemberg can make to successfully change this situation.

    https://www.gesundheitsindustrie-bw.de/en/article/news/vernachlaessigte-tropenkrankheiten-carsten-koehler-impulse-aus-baden-wuerttemberg
  • Article - 03/04/2019 team.jpg

    HKK Bionics empowers hand gripping functions

    A spin-off from the Ulm University of Applied Sciences is aiming to provide people whose hands have been paralysed due to accident or illness with a new kind of orthopaedic aid. Dominik Hepp and Tobias Knobloch are currently starting serial production of a hand orthosis prototype. The two medical engineers from Ulm, who founded HKK Bionics GmbH in 2017, plan to commence final tests in 2019.

    https://www.gesundheitsindustrie-bw.de/en/article/news/hkk-bionics-empowers-hand-gripping-functions
  • Article - 28/03/2019 The IT expert sitting at a meeting table.

    Supporting the human use of artificial intelligence

    Artificial intelligence is no longer a vision of the future, but is already in our midst: whether it is parking aids or search engines, we use the technology quite naturally in many areas of daily life. It promises new, unlimited opportunities, but also poses risks. Experts from the Integrata Foundation in Tübingen work on ethical issues and the human use of IT for improving the life of as many people as possible.

    https://www.gesundheitsindustrie-bw.de/en/article/news/supporting-the-human-use-of-artificial-intelligence
  • Press release - 26/03/2019

    EUR 3 million in series A for the growth and development of Cytena GmbH

    The High-Tech Gründerfonds (HTGF) and two private investors are convinced of the importance of single-cell isolation for the production of biopharmaceuticals and for genetic analysis in research and diagnostics. EUR 3 million will be invested in the further development of the technology, the expansion of the sales organization and in opening up further applications for Cytena’s single-cell printers.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/eur-3-million-in-series-a-for-the-growth-and-development-of-cytena-gmbh
  • Article - 22/03/2019 Prof. Lichter (left) and Prof. Schneeweiss, who run the Translational Breast Cancer Programme in Heidelberg, in the laboratory

    Personalised therapies for treating metastasing breast cancer

    Breast cancer is characterised by broad genetic diversity. Successful treatment is made even more difficult by the fact that, in advanced breast cancer, the properties of metastases often differ significantly from the primary tumour. The Heidelberg CATCH study is now collecting genetic profiles from patients' metastasis tissue samples, which can be used to tailor therapy to individual requirements.

    https://www.gesundheitsindustrie-bw.de/en/article/news/personalisierte-therapieansaetze-bei-metastasiertem-brustkrebs
  • Article - 18/03/2019 European Union flag in the wind.

    EHR and PHR: digital records in the German healthcare system

    EHRs, i.e. electronic health records (German: Patientenakte, ePA), are hailed as the key to increasing the quality of care. The Appointment Service and Supply Act (TSVG), adopted on 14th March 2019, requires the German statutory health insurance funds to provide policyholders with electronic health records from 1st January 2021 onwards.

    https://www.gesundheitsindustrie-bw.de/en/article/news/ehr-and-phr-digital-records-in-the-german-healthcare-system
  • Article - 05/03/2019 Schematic showing EBV particles in a blood vessel.

    Vaccination against oncogenic Epstein-Barr viruses

    Almost all humans are infected with Epstein-Barr viruses (EBV), which are linked to the development of benign diseases such as infectious mononucleosis as well as several cancers. Scientists from the German Cancer Research Center have developed a new strategy for creating a vaccine that targets different EBV virus life phases and has the potential to provide effective protection against EBV infection.

    https://www.gesundheitsindustrie-bw.de/en/article/news/vaccination-against-oncogenic-epstein-barr-viruses
  • Article - 21/02/2019 Teaser_Kellmeyer_Bild_2.PNG_.png

    Using neuromedical artificial intelligence responsibly

    Brain-computer interfaces are the latest developments in the neurotechnology field. They are used to record brain activity, which is then decoded with artificial intelligence techniques and converted into control signals for robots or computers. While this brings hope to severely paralysed people, it also implies risks due to the interest of companies like Google and Facebook in this type of data.

    https://www.gesundheitsindustrie-bw.de/en/article/news/using-neuromedical-artificial-intelligence-responsibly
  • Article - 07/02/2019 Ein Porträtfoto des Mediziners.

    Artificial intelligence in ophthalmology

    Retinal diseases such as age-related macular degeneration (AMD) are now treatable. However, it is hard to predict individual disease progression. A group of researchers at the University Eye Centre in Freiburg are currently developing a new system which is hoped will allay fears and improve therapy planning. The system uses artificial intelligence to predict therapeutic outcome from image and patient data. Initial results are already available.

    https://www.gesundheitsindustrie-bw.de/en/article/news/artificial-intelligence-in-ophthalmology
  • Article - 30/01/2019 Photo of Sven Benson.

    candidum – computer-assisted enzyme design

    Industry has been using enzymes for over a hundred years. While it initially had to content itself with natural enzymes, it is now increasingly possible to design tailor-made biocatalysts with specific properties. The start-up company candidum GmbH from Stuttgart promises to achieve this faster than ever before - mostly thanks to accelerated virtual screening.

    https://www.gesundheitsindustrie-bw.de/en/article/news/candidum-computer-assisted-enzyme-design
  • Article - 29/01/2019 RNA segments shown in black/grey, which are processed by grey and blue (represented as spheres) enzyme complexes.

    Targeted RNA editing with the body’s own enzyme activity

    Completely new possibilities for research and gene therapy became available following the development of the CRISPR/Cas method for targeted modification of the genome. However, treatment with molecular scissors is not without risk as potential errors are stored in the genome forever. Scientists from Tübingen have developed an alternative method in which the intervention takes place at the RNA level using the body's own enzymes and is thus…

    https://www.gesundheitsindustrie-bw.de/en/article/news/targeted-rna-editing-with-the-bodys-own-enzyme-activity
  • Press release - 28/01/2019 21359_de.jpg

    5,5 millions for project on smart matrices for knee cartilage repair

    A research project in cartilage regeneration, in which the Institute of Orthopaedic Research and Biomechanics at Ulm University participates together with partners from eight european countries, was recently financed by the European Commission with 5.5 million Euro. Named RESTORE, the project aims to create 3D matrices incorporating smart nanomaterials to repair knee cartilage lesions thereby reducing or delaying the onset of osteoarthritis,…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/55-millions-for-project-on-smart-matrices-for-knee-cartilage-repair
  • Article - 24/01/2019 The photo shows an ultra filtration system.

    Scientists to combat antibiotic-resistant bacteria in wastewater

    In Germany, around 1,500 tonnes of antibiotics per year are administered to humans and animals. As a result, more and more bacteria are developing resistance to common antibiotics. As part of HyReKA, a cooperative project funded by the BMBF, scientists led by Professor Thomas Schwartz from the KIT are investigating how antibiotic-resistant pathogens spread and how they can be prevented from doing so.

    https://www.gesundheitsindustrie-bw.de/en/article/news/scientists-to-combat-antibiotic-resistant-bacteria-in-wastewater
  • Expert interview - 16/01/2019 Photo of Holger Mettler

    Cybersecurity is an important issue for the pharmaceutical industry

    In an increasingly interconnected world, the pharmaceutical and biotechnology sectors need to be aware of cybersecurity threats in manufacturing. We talked about these threats with Holger Mettler who is in charge of computer system validation and cybersecurity at Exyte (formerly M + W), a global enterprise that designs, engineers and constructs complex manufacturing facilities and buildings for the life sciences industry.

    https://www.gesundheitsindustrie-bw.de/en/article/news/cybersecurity-is-an-important-issue-for-the-pharmaceutical-industry
  • Article - 10/01/2019 Cover of the fourth gene technology report.

    Stocktaking and recommendations for action: the BBAW’s fourth gene technology report

    In the new gene technology report, the interdisciplinary working group of the Berlin-Brandenburg Academy of Sciences (BBAW) takes stock of gene technology developments in Germany during the past few decades, and discusses the societal, legal and ethical challenges associated with these technologies in the future. The report is highly topical due to the controversy surrounding the ruling of the European Court of Justice on CRISPR/Cas9 genome…

    https://www.gesundheitsindustrie-bw.de/en/article/news/stocktaking-and-recommendations-for-action-the-bbaws-fourth-gene-technology-report
  • Company profile - 09/01/2019 Schematic showing the molecular structure of calicheadmicin at the target of the enzyme, i.e. DNA, that is also shown schematically. Figure: HQS Quantum Simulations

    HQS Quantum Simulations for industrial quantum mechanics applications

    The door to the quantum world is opening wider and wider. Behind it is a whole new view of materials and molecules. Quantum mechanics applications not only benefit science, they also offer huge economic potential. The Karlsruhe start-up HQS Quantum Simulations is playing a pioneering role in quantum simulations for the chemical and pharmaceutical industries.

    https://www.gesundheitsindustrie-bw.de/en/article/news/hqs-quantum-simulations-for-industrial-quantum-mechanics-applications
  • Company profile - 19/12/2018 The photo shows a lateral view of a typical printer with a red blister pack to symbolise the suitability of printers for the production of drugs.

    With DiHeSys into integrated digital healthcare

    The founders and partners of DiHeSys have big ambitions: "We have to build a complete ecosystem around the patient," says Dr. Markus Dachtler, managing director of DiHeSys. The company develops products and services for an industry in transition, provides answers to trends such as personalized medicine, 2D- and 3D-printing technologies and platform technologies. The company’s motto: no isolated solutions, but a comprehensive range of…

    https://www.gesundheitsindustrie-bw.de/en/article/news/with-dihesys-into-integrated-digital-healthcare
  • Anniversary - 12/12/2018 Teaser_Bild_15Jahre_CG_BIOPRO_Webversion.jpg

    15 years of BIOPRO: Pooling competencies – pushing innovations

    This is the leitmotif of BIOPRO Baden-Württemberg GmbH, which was founded in 2003. 15 years is a good time to pause for a moment and take a look at BIOPRO’s work and achievements. As a central point of contact and wholly-owned subsidiary of the Baden-Württemberg government whose main objective is to promote networking, BIOPRO knows only too well that progress is not made alone, but in collaboration with others.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/15-years-of-biopro-pooling-competencies-pushing-innovations
  • Press release - 10/12/2018 Trumpp_Andreas.jpg

    High distinction for stem cell researcher Andreas Trumpp

    This year's State Research Prize of Baden-Württemberg awarded for outstanding achievements in applied research goes to Andreas Trumpp from the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM). Theresia Bauer, State Minister of Science, Research and the Arts, presented the award, which carries a monetary prize of €100.000, at a festive ceremony on December 10, 2018.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/high-distinction-for-stem-cell-researcher-andreas-trumpp
  • Press release - 03/12/2018

    SpinDiag closes second financing round of EUR 3.0 million (USD 3.4 million) to complete product development of its point-of-care screening system for antibiotic-resistant bacteria

    One year after its seed financing, SpinDiag GmbH closes a second financing round of EUR 3 million (USD 3.4 million) as planned. The financing will enable SpinDiag to complete the product development of its first product for screening for antibiotic-resistant bacteria and to start clinical trials. This will pave the way for regulatory approval in the EU.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/spindiag-closes-second-financing-round-of-eur-30-million-usd-34-million-to-complete-product-development-of-its-point-of-care-scr
  • Press release - 29/11/2018

    Hattrick in Freiburg

    Three researchers at the MPI for Immunobiology and Epigenetics receive millions in funding from the European Research Council. Dominic Grün, Nicola Iovino and Ritwick Sawarkar from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg will each be awareded one of the prestigious Consolidator Grants of the European Research Council. This means that 6 million euros in funding will go to fundamental research in Freiburg over the next…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/hattrick-in-freiburg
  • Plant breeding - 19/11/2018 Teaser_Nicotiana_tabacum_001.png

    Tobacco for health

    Plants can be used as biofactories to produce valuable active ingredients such as proteins, antibodies, dyes or vaccines. A project called Newcotiana aims to re-position the existent tobacco industry infrastructure. The project partners, including Prof. Dr. Holger Puchta from the Karlsruhe Institute of Technology, use modern breeding methods to develop tobacco varieties with new capabilities.

    https://www.gesundheitsindustrie-bw.de/en/article/news/tobacco-for-health
  • Company profile - 19/11/2018 The photo shows a monitor with six radiological images.

    CHILI GmbH – teleradiology pioneers

    Teleradiology is the most advanced telemedicine application in Germany. CHILI GmbH from Dossenheim is one of the companies that has contributed to driving the development of teleradiology forward. The company specialises in PACS and teleradiology systems and helps connect clinics and physicians.

    https://www.gesundheitsindustrie-bw.de/en/article/news/chili-gmbh-teleradiology-pioneers
  • Biosensor - 13/11/2018 Schematic showing the workflow that is required for obtaining a test result with paper strip, pipette, darkness and camera. A test result showing circles with different shades of blue and red.

    Rapid medical test for at-home use

    For quite a number of illnesses, patients need to have the concentrations of the medications they are taking and their blood metabolites checked on a regular basis, which can make life rather difficult. Researchers at the Max Planck Institute for Medical Research in Heidelberg have now developed a test based on the firefly enzyme luciferase. This enzyme can be used to quickly and cheaply measure parameters of interest.

    https://www.gesundheitsindustrie-bw.de/en/article/news/rapid-medical-test-for-at-home-use
  • Article - 30/10/2018 Zu sehen ist eine Karte der trinationalen Region am Oberrhein, auf der die verschiedenen Universitäten und Forschungseinrichtungen markiert sind.

    Eucor – bringing the European Campus to life

    Enrolling at one university and being able to use the services of a total of five universities is unique in the European Research Area. A model project called Eucor - The European Campus offers students and young scientists this opportunity at universities in the Germany-France-Switzerland border triangle, which simultaneously acts as a borderless academic area for the sciences.

    https://www.gesundheitsindustrie-bw.de/en/article/news/eucor-bringing-the-european-campus-to-life
  • Article - 29/10/2018 Bernhard Hirt, stehend vor einem anatomischen Modell eines Menschen, hält drei Glaskolben in den Händen.

    Aminolipine: formaldehyde-free substitute for preserving biological tissues

    For almost 125 years, undertakers as well as physicians in the fields of anatomy and pathology have used formaldehyde to preserve biological tissue and whole cadavers. Yet, formaldehyde is highly toxic and linked to cancer. A team led by Prof. Dr. Bernhard Hirt from the Institute of Clinical Anatomy and Cell Analysis at the University Hospital in Tübingen has developed a formaldehyde-free replacement substance.

    https://www.gesundheitsindustrie-bw.de/en/article/news/aminolipine-formaldehyde-free-substitute-for-preserving-biological-tissues
  • Expert interview - 17/10/2018 Porträtfoto von Dr. Ralf Schumacher

    Biologicals are becoming increasingly important to Boehringer Ingelheim

    Biopharmaceuticals are playing an increasingly important role in Boehringer Ingelheim’s development pipeline. Visible evidence of this is the company’s Biologicals Development Centre (BDC) that is currently being constructed in Boehringer Ingelheim’s Biberach plant and will bring the company’s process development under one roof by early 2020. Walter Pytlik from BIOPRO talked with Dr. Ing. Ralf Schumacher about the new centre.

    https://www.gesundheitsindustrie-bw.de/en/article/news/biologicals-are-becoming-increasingly-important-to-boehringer-ingelheim
  • Article - 10/10/2018 Eine Frau, die sich das schildkrötenförmige weiß-blaue Gerät an die Brust drückt.

    BABYBE GmbH: Premature babies in contact with mum around the clock

    It used to be believed that premature babies needed as much rest as possible. However, studies have since shown that this is not the case at all. According to these studies, the brains of premature babies need to be stimulated 24 hours a day, ideally close to the mother, to ensure healthy development. The Stuttgart-based start-up BABYBE GmbH has developed a special gel mattress that enables babies to perceive their mother’s heartbeat and voice…

    https://www.gesundheitsindustrie-bw.de/en/article/news/babybe-gmbh-premature-babies-in-contact-with-mum-around-the-clock
  • Article - 02/10/2018 Microscope image of a kidney section, marked with yellow circles.

    Artificial intelligence in the life sciences: machines as assistants

    Artificial intelligence is currently one of the most innovative issues, but also one of the most controversial research areas. It already has a firm footing in many areas of our everyday life and often we are not even aware of it. Artificial intelligence has long been an integral part of many processes in research and diagnostics in medicine and the life sciences – and it will be even more widely used in the future.

    https://www.gesundheitsindustrie-bw.de/en/article/news/artificial-intelligence-in-the-life-sciences-machines-as-assistants
  • Press release - 27/09/2018

    Three new Clusters of Excellence for Tübingen

    University takes next hurdle in the German government’s Excellence Strategy funding program. The University of Tübingen is to have three new Clusters of Excellence.As part of the German government’s Excellence Strategy funding forhigher education research, Tübingen will host new outstanding research networks starting in January 2019. Representatives of Germany’s higher education policymakers announced the decision in Bonn on Thursday.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/three-new-clusters-of-excellence-for-tuebingen
  • Press release - 27/09/2018

    One hundred percent success

    Two Clusters of Excellence for the University of Freiburg: Biological Signalling Studies and Bioinspired Materials Research. It is a major boost to cutting-edge research in Freiburg: in the current Excellence Strategy competition, scientists at the University of Freiburg have been granted two Clusters of Excellence, CIBSS – Centre for Integrative Biological Signalling Studies, and livMatS – Living, Adaptive and Energy-autonomous Materials…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/one-hundred-percent-success
  • Industry report 2018 - 27/09/2018 Branchenreport_Gesundheitsindustrie__Zahlen_und_Fakten_fur_Baden-Wurttemberg_Titelseite_U1.jpg

    The healthcare industry – the innovation driver of the 21st century: opportunities and challenges

    BIOPRO Baden-Württemberg’s new industry report entitled "The Healthcare Industry 2018: Facts and Figures for Baden-Württemberg" has just been published in both German and English. The topic neatly dovetails with the state’s political activities. An evaluation of the region carried out on behalf of the Baden-Württemberg government has clearly recognised the importance of the healthcare sector as a driver of innovation.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/the-healthcare-industry-the-innovation-driver-of-the-21st-century
  • Cancer immunotherapy - 06/09/2018 Schematic showing the so-called breakthrough event as well as the expansion and invasion stages of cells during carcinogenesis.

    The immunogenicity of tumours and the development of new cancer medicines

    Microsatellite-unstable cancers are characterised by a large number of mutations within short repetitive DNA sequence regions, and can form novel peptides that the human immune system recognises as neoantigens. These cancers represent a starting point for the development of vaccines to prevent them appearing at an early stage of development. Microsatellite instability is particularly frequent in colon and cervical cancers.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-immunogenicity-of-tumours-and-the-development-of-new-cancer-medicines
  • Dossier - 28/08/2018 Woman wearing a white lab coat in a laboratory looking at a tube she is holding in her hand.

    With molecular diagnostics to biomarker-based personalised therapy

    Diagnosing suitable biomarkers is a prerequisite for tailoring personalised therapies to patient heterogeneity. Genetic tests and genome sequencing play a key role in these diagnoses. Up until now, personalised therapy has achieved the greatest success in the field of oncology. However, personalised treatments are also gaining in importance for treating other diseases.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/with-molecular-diagnostics-to-biomarker-based-personalised-therapy
  • Press release - 27/08/2018

    Affimed Announces Collaboration with Genentech to Develop Novel NK Cell Engager-based Immunotherapeutics for Multiple Cancer Targets

    Affimed will receive $96 million upfront and committed funding and is eligible for up to an additional $5.0 billion including milestone payments, and royalties on sales.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/affimed-announces-collaboration-with-genentech-to-develop-novel-nk-cell-engager-based-immunotherapeutics-for-multiple-cancer-tar
  • Article - 21/08/2018 Cells stained blue and red.

    Parkinson's disease: vitamin B3 has a positive effect on nerve cells

    Parkinson's disease is one of the most common neurodegenerative diseases in the world. There are around 4.1 million sufferers worldwide. It is characterised by motor impairments that result from the death of certain nerve cells in the brain. Researchers at the University of Tübingen have now discovered that vitamin B3 has a positive effect on damaged nerve cells and can boost their energy metabolism.

    https://www.gesundheitsindustrie-bw.de/en/article/news/parkinsons-disease-vitamin-b3-has-a-positive-effect-on-nerve-cells
  • Press release - 14/08/2018

    Triple ERC success for DKFZ junior researchers

    The European Research Council (ERC) awards Starting Grants to support excellent young scientists when they are starting an independent science career. In this year's round of proposals, three scientists from the German Cancer Research Center (DKFZ) have been chosen at once for the prestigious award: Ana Banito, Fabian Erdel and Moritz Mall.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/triple-erc-success-for-dkfz-junior-researchers
  • Article - 14/08/2018 Photo of the developer team (from left to right): Jonas Pfeil, Daniel
Geiger and Tobias Neckernuß. An optical measurement system can be seen on the right-hand side. Photo: Daniel Geiger

    Simple and fast: new optical method for analysing living cells

    The junior researchers Dr. Daniel Geiger, Tobias Neckernuß and Jonas Pfeil from Ulm have developed an innovative method for non-contact real-time analysis of cells and other particles. The analysis involves low data rates and correspondingly little effort. This is what makes the method so attractive for medical applications.

    https://www.gesundheitsindustrie-bw.de/en/article/news/simple-and-fast-new-optical-method-for-analysing-living-cells
  • Expert interview - 08/08/2018 Das Bild zeigt das Brustbild des ALS-Forschers, und Ärztlichen Direktors der Neurologischen Klinik der Uni Ulm, Prof. Albert Ludolph. Der Neurologe ist Sprecher des DZNE-Standorts Ulm.

    Ludolph: diagnosing and treating neurodegenerative disorders

    Ulm has long been a world leader in diagnosing and treating rare neurological disorders, notably amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Huntington's disease (HD). We spoke with Professor Albert C. Ludolph, spokesperson for the Ulm DZNE site, medical director of the Clinic for Neurology at the RKU (University and Rehabilitation Clinics of Ulm) and world-renowned ALS researcher.

    https://www.gesundheitsindustrie-bw.de/en/article/news/ludolph-diagnosing-and-treating-neurodegenerative-disorders
  • Company profile - 31/07/2018 Photo of the physicist.

    Acousia Therapeutics: medicines for deafness

    Deafness is one of the most common sensory disorders in the world: in Germany alone, around eleven million people suffer from hearing loss. So far there is no real therapy, the symptoms can only be alleviated to a greater or lesser degree. This is what researchers from the Tübingen-based company Acousia Therapeutics want to change: they have identified drug candidates that can protect sensory hair cells and support their function.

    https://www.gesundheitsindustrie-bw.de/en/article/news/acousia-therapeutics-medicines-for-deafness
  • Press release - 27/07/2018 PM_KIT_erklimmt_naechste_Stufe_Bund_und_Land_treiben_Weiterentwicklung_entschlossen_voran.jpg

    KIT Takes the Next Step: Federal and State Ministries Determined to Push KIT’s Further Development

    To further support and develop the scientific capacity of Karlsruhe Institute of Technology (KIT), the federal and state governments are determined to take the courageous merger of 2009 to the next level. During their joint visit of KIT today, Federal Minister of Education and Research Anja Karliczek and the Baden-Württemberg Minister for Science, Research and the Arts Theresia Bauer agreed on the next steps.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/kit-takes-the-next-step-federal-and-state-ministries-determined-to-push-kits-further-development
  • Company profile - 26/07/2018 Screenshot of the pneumonia evid.one app.

    evid - therapy recommendations at a glance

    There are over 700 treatment guidelines in Germany alone, and each is up to several hundred pages long. Can doctors still stay on top of things? A start-up company from Mannheim called evid is developing a software that can retrieve relevant therapy recommendations for individual patients from the huge pile of paperwork. In March 2018, the founding trio won first place of the eHealthForum Freiburg start-up competition.

    https://www.gesundheitsindustrie-bw.de/en/article/news/evid-therapy-recommendations-at-a-glance
  • Funding

    Future Insight Prize

    Funding programme, Funded by: Merck KGaA, sb_search.searchresult.label.programSubmissionDate: 31/12/2022
    https://www.gesundheitsindustrie-bw.de/en/database/funding/future-insight-prize
  • The Baden-Württemberg healthcare industry

    Baden-Württemberg – an attractive business location

    Baden-Württemberg, the state of inventors and thinkers, is one of the leading economic regions in Germany and Europe thanks to an economic landscape that incorporates many small- and medium-sized businesses. The state’s innovative strength is partly based on the scientific excellence of university and non-university research institutions and innovative companies, and partly on its attractiveness as a base for creating and developing companies.…

    https://www.gesundheitsindustrie-bw.de/en/location/location-bw
  • Press release - 20/07/2018

    First closing at SHS: Medical technology investor raises over €90 million for its fifth fund

    SHS Gesellschaft für Beteiligungsmanagement has received capital commitments of over €90 million in its fifth fund's first closing. The fifth generation of SHS funds is also focused on the life sciences and medical technology sector, and thus on the growing global healthcare market with innovative and strong players, especially in Germany and Switzerland.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/first-closing-at-shs-medical-technology-investor-raises-over-90-million-for-its-fifth-fund
  • Stem cell research - 12/07/2018 The figure shows the loop-shaped region of a chromosome through which the blood enhancer cluster BENC and the Myc gene come into close spatial vicinity. The blood enhancer cluster (enlarged) consists of nine gene enhancers that are arranged in individual modules one after the other on the chromosome.

    The role of stem cell dormancy in regeneration and cancer

    Scientists at the HI-STEM stem cell institute in Heidelberg have shown that the stem cells responsible for replenishing blood cells have the greatest potential of self-renewal of any other stem cells. However, they are normally in a dormant state, and only become active upon exposure to certain stress factors. An oncogene called MYC controls the stem cells' transition from dormancy to active self-renewal.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-role-of-stem-cell-dormancy-in-regeneration-and-cancer
  • Press release - 04/07/2018 The collagen membrane „Collagen Cell Carrier“ is thin, elastic, yet robust and biocompatible.

    Phase-I-trial approved for novel stem cell therapy for patients with ischemic cardiomyopathy

    Viscofan BioEngineering, the biomedical business unit of the world market leader for collagenous sausage casings Viscofan announced today that the Spanish Agency for Medicines (AEMPS) has given green light to carry out a clinical phase-I-trial with Viscofan BioEngineering’s first product for regenerative medicine. The novel therapy consisting of stem cells on a collagenous carrier membrane can now be tested on ten patients suffering from severe…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/phase-i-trial-approved-for-novel-stem-cell-therapy-for-patients-with-ischemic-cardiomyopathy
  • Article - 03/07/2018 Laboratory technician wearing a white lab coat and data goggles, sitting at a hood, pipetting liquid into a laboratory vessel.

    The digital laboratory is picking up speed

    A new team at the Fraunhofer IPA is developing digital laboratory systems to support industrial partners in planning and managing laboratory processes. This benefits companies in terms of quality assurance, economic efficiency and, notably, ergonomic improvements to the work place.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-digital-laboratory-is-picking-up-speed
  • Expert interview - 26/06/2018 Photo of Dr. med. Dr. rer. nat. Saskia Biskup.

    Genome analyses: "Germany lags behind dramatically"

    Around 6,000 genetic diseases can be diagnosed using genetic tests. Genetic testing enables the accurate identification of diseases especially when symptoms are unclear, and also allows statements to be made about disease progression. However, restrictive regulations considerably hinder the use of genetic diagnostics. BIOPRO spoke with Dr. Dr. Saskia Biskup, a human genetics specialist and co-founder of the Tübingen-based company CeGaT.

    https://www.gesundheitsindustrie-bw.de/en/article/news/genome-analyses-germany-lags-behind-dramatically
  • Article - 13/06/2018 The photo shows a dermatoscope that is being held like a small torch over a patient's forearm.

    TeleDerm: Rapid help from a dermatologist via teleconsultation

    Some geographical locations have relatively few specialist medical practices. Getting an appointment with a specialist if you live in such areas might mean a long wait or a long journey. A study being carried out at the University of Tübingen is looking to improve this situation: the TeleDerm project involves dermatologists using telemedicine to assess skin disorders from images taken by GPs.

    https://www.gesundheitsindustrie-bw.de/en/article/news/telederm-rapid-help-from-a-dermatologist-via-teleconsultation
  • Article - 06/06/2018 Der Roboter ist modular aufgebaut und kann so für verschiedene Anwendungen genutzt werden.

    Robots for assisting with care and treatment in nursing homes and hospitals

    Robotic systems have great potential in the healthcare sector. For example, intelligent care aids, such as robotic technologies, extended care trolleys and lifters make life easier for nursing home and hospital staff. Mobile robots that assist with transport tasks or guiding people can help patients become more independent.

    https://www.gesundheitsindustrie-bw.de/en/article/news/robots-for-assisting-with-care-and-treatment-in-nursing-homes-and-hospitals
  • Article - 29/05/2018 Cells stained with a green fluorescing dye, on a computer keyboard.

    ITAS – Assessing the impact of life science technologies

    The Karlsruhe Institute for Technology Assessment and Systems Analysis (ITAS) is one of the largest and most renowned institutions in Germany involved in evaluating scientific and technological developments. The institute assesses the impacts and possible effects of new methods from a wide range of scientific fields - including the life sciences.

    https://www.gesundheitsindustrie-bw.de/en/article/news/assessing-the-impact-of-life-science-technologies
  • Article - 23/05/2018 Electron microscope image of a bacteriophage.

    Bacteriophages as alternatives to antibiotics

    Multidrug-resistant bacteria are resistant to many existing antibiotics and can be difficult to treat. There are increasing numbers of them worldwide. Although novel antibiotics are being developed, there are far too few of them to tackle the rise of multidrug-resistant bacteria. In Eastern Europe, doctors have been treating bacterial infections with viruses that infect bacteria, so-called bacteriophages, for almost 100 years.

    https://www.gesundheitsindustrie-bw.de/en/article/news/bacteriophages-as-alternatives-to-antibiotics
  • Article - 16/05/2018 Porträtbild von Prof. Bardutzky.

    Telemedical neurology council helps speed up stroke treatment

    Stroke units save lives because specialist treatment is absolutely crucial for stroke patients. However, not all clinics have neurological specialists available 24/7, so telemedicine provides a good solution to the problem. Studies show that telemedical consultations can considerably improve the treatment of stroke patients.

    https://www.gesundheitsindustrie-bw.de/en/article/news/telemedical-neurology-council-helps-speed-up-stroke-treatment
  • Article - 25/04/2018 Prevalence of malaria in Africa.

    Resistance, immunity and malaria vaccination

    People who have survived a malaria infection often develop immunity to the disease. International malaria research is aimed at exploiting a person's natural immunity in order to treat malaria effectively and avoid resistance to previously effective drugs. These new approaches also raise hopes that one day countries at high risk of malaria may be able to eradicate the devastating disease.

    https://www.gesundheitsindustrie-bw.de/en/article/news/resistance-immunity-and-malaria-vaccination
  • Article - 19/04/2018 Female volunteer whose hand is connected to a robotic device that opens her hand while receiving magnetic stimuli via magnetic coils close to her head. The photo shows a member of Gharabaghi's team moving the magnetic coils over the volunteer's head.

    New combination therapy for treating stroke patients

    30 to 40 percent of all stroke patients suffer from persistent signs of paralysis that prevents them from using the affected hand. The innovative combination of two non-invasive treatment methods is a therapeutic approach with considerable potential for treating severely impaired patients.

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-combination-therapy-for-treating-stroke-patients
  • Article - 05/04/2018 Translational cancer research is able to bridge the valley of death. The drawing shows a bridge spanning the two valleys of death in medical research - one between preclinical and clinical research and another between the clinical efficacy of drugs as demonstrated by clinical trials and the evidence of real benefits for patients and society.

    Crossing the valley of death with translational cancer research

    It can take many decades before promising research results become therapies that have a positive effect on cancer patients. Most research projects go adrift somewhere between the laboratory and the bedside in the so-called "valley of death". Projects carried out at the DKFZ show that translational cancer research actually works.

    https://www.gesundheitsindustrie-bw.de/en/article/news/crossing-the-valley-of-death-with-translational-cancer-research
  • Press release - 03/04/2018 Simon Raffel, Lars Velten and Simon Haas.

    Double success for Heidelberg stem cell researchers

    Two awards at once, both carrying high monetary prizes, go to young researchers from the Heidelberg Institute for Stem Cell Research and Experimental Medicine (HI-STEM) at the German Cancer Research Center (DKFZ): Simon Raffel will receive the 2018 Walter Schulz Prize. Simon Haas will share the 2018 Otto Schmeil Prize with his colleague Lars Velten from EMBL.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/double-success-for-heidelberg-stem-cell-researchers
  • Article - 28/03/2018 Fluorescent microscope image of a human cell nucleus in the bottom right-hand corner. The nucleus contains numerous yellow dots. These represent signals that are emitted by methylated DNA sequences. The molecular structure of the sensor components is shown schematically in the top left-hand corner. We can see an anchor domain (orange) bound to DNA, a detector domain bound to a chromatin modification (red), and the active fluorophore (green).

    New method for analysing epigenetic modifications - in the service of medical progress

    It is not just genetic factors that influence developmental processes and diseases; it is becoming increasingly evident that epigenetic changes play a major role too. Thanks to a new method developed at the University of Stuttgart, epigenetic processes can now be investigated in living cells.

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-method-for-analysing-epigenetic-modifications-in-the-service-of-medical-progress
  • Big Data - 26/03/2018 Schematic showing how data of a patient from different sources such as imaging and molecular diagnostics along with expert comments are combined and used for making a decision.

    Eliciting reliable information from big data with classifiers and multimodal data fusion

    Prof. Hans A. Kestler knows a great deal about large amounts of data. He heads up the Institute of Medical Systems Biology at the University of Ulm and is constantly inundated with cooperation enquiries from clinicians. On behalf of BIOPRO, Walter Pytlik asked him whether the conditions for using big data more in biomedical research are already largely present.

    https://www.gesundheitsindustrie-bw.de/en/article/news/eliciting-reliable-information-from-big-data-with-classifiers-and-multimodal-data-fusion
  • Alternative to animal experiments - 21/03/2018 The long-term expectation is to be able to several organs on a single chip.

    Drug tests using miniature organs

    At present, potential new drugs have to be tested on animals before they can be used on humans. However, results obtained from animals are not always transferrable to the situation in humans, which is why researchers around the world have long been seeking alternatives. Miniature human organs that can be used to test the efficacy of potential human drugs might provide a solution.

    https://www.gesundheitsindustrie-bw.de/en/article/news/drug-tests-using-miniature-organs
  • Article - 19/03/2018 Handling holding a pipette into a plastic bottle containing pink culture medium.

    Regenerative medicine: curing rather than simply treating diseases

    Some scientists refer to the latest developments in the field of regenerative medicine as the "next revolution in medicine". With the help of gene therapies or stem cells, regenerative medicine aims not only to treat disease symptoms, but to cure them at source. Some approaches are already being used to treat patients and several others are close to application.

    https://www.gesundheitsindustrie-bw.de/en/article/news/regenerative-medicine-curing-rather-than-simply-treating-diseases
  • Article - 14/03/2018 Bild1_Prof.KnebelDoeberitz.jpg

    Patent versus publication: setting up start-ups in the sciences

    When it comes to universities as start-up incubators, the Massachusetts Institute of Technology (MIT) in the USA is often used as a prime example of entrepreneurial impact. Well over 100 high-tech spin-offs have been set up in the vicinity of the renowned university. Many German universities also offer attractive conditions for scientists with an entrepreneurial spirit.

    https://www.gesundheitsindustrie-bw.de/en/article/news/patent-versus-publication-setting-up-start-ups-in-the-sciences
  • Big Data - 13/03/2018 Viegas-User-Activity-on-Wikipedia.png

    “More data does not automatically imply more knowledge“

    In Germany, one of the big names in evidence-based medicine is Prof. Dr. rer. nat. Gerd Antes, co-director of Cochrane Germany. In the following interview, Antes talks about the hype surrounding big data, warns against false promises and reminds us about what is taken for granted.

    https://www.gesundheitsindustrie-bw.de/en/article/news/more-data-does-not-automatically-imply-more-knowledge
  • Article - 08/03/2018 The three company founders crouching in front of a poster with an ello and the company logo.

    Investors wanted: can crowdfunding get the electric walking frame up and running?

    If e-bikes make getting around easier, why shouldn't it be possible to apply the same principle to walking frames? That's exactly the question that three young company founders from Stuttgart asked, which led to the development of an electric walking frame called ello. This new walking frame allows users to cope with gradients and kerbs easily and without too much effort.

    https://www.gesundheitsindustrie-bw.de/en/article/news/investors-wanted-can-crowdfunding-get-the-electric-walking-frame-up-and-running
  • Dossier - 06/03/2018 The diagram shows a huge tidal wave with a mighty crest breaking on a person with a bowed head. Along the wave are keywords that reflect the opportunities (optimisation, data management, research, precision medicine) and risks (databases, monitoring) of using big data.

    Big data - the big promise of the new digitised world

    Big data is a widely used buzzword in today's information era. The use of big data in the digital world presents both an opportunity and a risk. Mass data is now used and analysed in almost all areas of life. Even the healthcare sector is undergoing extensive digitisation.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/big-data-the-big-promise-of-the-new-digitised-world
  • Article - 21/02/2018 The diagram highlights the importance of the MKK4 kinase enzyme in people with liver injury. Activation of MKK4 can lead to hepatic failure and death, or severe fibrosis. This is shown on the left-hand side of the diagram. Inhibition of MKK4 accelerates the replication of hepatocytes and prevents their apoptosis, thereby permitting successful regeneration of the liver. In the worst case, inhibition of MKK4 leads to light fibrosis only. The result of MKK inhibition is shown on the right-hand side of the diagram.

    HepaRegeniX – a start-up is taking it up a step!

    HepaRegeniX, a biotech company founded in 2016, specialises in developing drugs that restore the regenerative capacity of diseased livers. The three founders of the biotech start-up, Prof. Dr. Lars Zender, Prof. Dr. Stefan Laufer and Dr. Wolfgang Albrecht, anticipate starting clinical testing of the first drug candidate in 2019.

    https://www.gesundheitsindustrie-bw.de/en/article/news/heparegenix-a-start-up-is-taking-it-up-a-step
  • Press release - 21/02/2018 Michael Baumann, Chairman and Scientific Director of the German Cancer Research Center (DKFZ) in Heidelberg, receives the 2017 German Cancer Award in the category "Translational Research".

    German Cancer Award for Michael Baumann

    Michael Baumann, Chairman and Scientific Director of the German Cancer Research Center (DKFZ) in Heidelberg, receives the 2017 German Cancer Award in the category "Translational Research". The science award, which is sponsored by the German Cancer Society and the German Cancer Foundation, is one of the most prestigious distinctions in cancer medicine in Germany.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/german-cancer-award-for-michael-baumann
  • Article - 20/02/2018 Anopheles mosquito biting the skin.

    New strategies against malaria

    Malaria, which is a mosquito-borne disease caused by Plasmodium parasites, is still one of the worst infectious human diseases. The parasites have developed resistance against previously effective drugs and new strategies to combat malaria are urgently needed.

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-strategies-against-malaria
  • Article - 14/02/2018 The photo shows the biologist in front of the microscope with cell cultures in pink culture medium.

    Animal-free diabetes research with the pancreas chip

    Quite a number of promising drug candidates for the treatment of diabetes are currently in the pharmaceutical pipeline, including innovative drugs that can stimulate the regeneration of insulin-producing pancreatic cells. However, they will have to be safety tested in animals. Scientists from Ulm University Hospital have now begun to develop a pancreatic chip from stem cells.

    https://www.gesundheitsindustrie-bw.de/en/article/news/animal-free-diabetes-research-with-the-pancreas-chip
  • Press release - 13/02/2018

    CureVac to Pursue Innovative mRNA Vaccines Against Flu and Malaria

    Extends ongoing collaboration with Bill & Melinda Gates Foundation with award of two new grants. CureVac AG, a fully-integrated biopharmaceutical company pioneering the field of mRNA-based drugs, today announced the awarding of two new grants from the Bill & Melinda Gates Foundation.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/curevac-entwickelt-innovative-mrna-impfstoffe-gegen-influenza-und-malaria

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